Kwon, Ria and Chang, Yoosoo and Kim, Yejin and Cho, Yoosun and Choi, Hye Rin and Lim, Ga-Young and Kang, Jeonggyu and Kim, Kye-Hyun and Kim, Hoon and Hong, Yun Soo and Park, Jihwan and Zhao, Di and Rampal, Sanjay and Cho, Juhee and Guallar, Eliseo and Park, Hyun-Young and Ryu, Seungho (2022) Alcohol consumption patterns and risk of early-onset vasomotor symptoms in premenopausal women. Nutrients, 14 (11). ISSN 2072-6643, DOI https://doi.org/10.3390/nu14112276.
Full text not available from this repository.Abstract
The role of alcohol consumption in the risk of vasomotor symptoms (VMS), the most cardinal climacteric symptoms, is not well established. We examined their relationship with early-onset VMS among premenopausal women. Moderately-to-severely bothersome VMS, the primary outcome, was assessed using the Korean version of the Menopause-Specific Quality of Life questionnaire. The alcohol consumption categories included lifetime abstainer, former drinker, or current drinker, categorized as light, moderate, heavy, and very heavy. Compared with the lifetime-abstinence (reference), the multivariable-adjusted odds ratio (95% CIs) for prevalent VMS in alcohol consumption of <10, 10-19, 20-39, and >= 40 g/day were 1.42 (1.02-1.99), 1.99 (1.27-3.12), 2.06 (1.19-3.57), and 3.52 (1.72-7.20), respectively (p trend <0.01). Compared with the lifetime-abstinence, the multivariable-adjusted hazard ratios (95% CIs) for incident bothersome VMS among average alcohol consumption of <10, 10-19, 20-39, and >= 40 g/day were 1.10 (0.85-1.41), 1.03 (0.70-1.51), 1.72 (1.06-2.78), and 2.22 (1.16-4.23), respectively (p trend = 0.02). Increased alcohol consumption positively and consistently showed a relationship with increased risk of both prevalent and incident early-onset VMS. Refraining from alcohol consumption may help prevent bothersome VMS in premenopausal women.
| Item Type: | Article |
|---|---|
| Funders: | Korea Centers for Disease Control and Prevention [Grant No:2014ER630200], Korea Centers for Disease Control and Prevention [Grant No:2017ER630200], Korea Centers for Disease Control and Prevention [Grant No:2020-ER7102-00], Korea Centers for Disease Control and Prevention [Grant No:2020ER710201], Korea Centers for Disease Control and Prevention [Grant No:2020ER710202 |
| Uncontrolled Keywords: | Alcohol consumption; Hot flashes; Night sweats; Vasomotor symptoms; Premenopausal women |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Social & Preventive Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 12 Oct 2023 04:04 |
| Last Modified: | 12 Oct 2023 04:04 |
| URI: | http://eprints.um.edu.my/id/eprint/42141 |
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