Early versus standard tracheostomy in ventilated patients in neurosurgical intensive care unit: A randomized controlled trial

Goo, Zhen Qiang and Muthusamy, Kalai Arasu (2022) Early versus standard tracheostomy in ventilated patients in neurosurgical intensive care unit: A randomized controlled trial. Journal of Clinical Neuroscience, 98. pp. 162-167. ISSN 0967-5868, DOI https://doi.org/10.1016/j.jocn.2022.02.011.

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Abstract

Introduction: Tracheostomy is performed in patients with prolonged mechanical ventilation, who suffered catastrophic neurologic insult or upper airway obstruction. Thus far, there is no consensus on the optimal timing in performing a tracheostomy. This study aims to test whether early tracheostomy in mechanically ventilated patients in a neurosurgical setting would be associated with a shorter time of mechanical ventilation as compared to standard tracheostomy. Methods: This single-center prospective randomized controlled trial was conducted at University Malaya Medical Centre from July 2019 to July 2021. The likelihood of prolonged ventilation was determined objectively using the TRACH score and the patient's clinical presentation. The outcomes measured were days of mechanical ventilation post-tracheostomy, days of neuro-intensive care unit stay, and days of hospital stay. Tracheostomyrelated complications were collected. The data collected were analyzed using Statistical Package for the Social Sciences version 25 for Windows (SPSS Inc., Chicago, IL, USA). Results: In all, 39 patients were randomly assigned. Of these, 20 were allocated to the early tracheostomy group (ET) and 19 were allocated to the standard tracheostomy group (ST). The demographic characteristics were similar between the groups. The primary outcome, mean (SD) days of mechanical ventilation post-tracheostomy, was statistically different in the 2 groups- early 11.9 (9.3) days, standard 18.9 (32.5) days; p = 0.014. There were comparable tracheostomy-related complications in both groups. Conclusion: Early tracheostomy is associated with a shorter duration of mechanical ventilation in a neurosurgical intensive care unit setting.

Item Type: Article
Funders: None
Uncontrolled Keywords: Tracheostomy; Prolonged ventilation; Mechanical ventilation
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 19 Oct 2023 03:25
Last Modified: 19 Oct 2023 03:25
URI: http://eprints.um.edu.my/id/eprint/42057

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