Experience in managing glaucoma filtration surgery complications with oral doxycycline: A case series

Yong, Geng-Yi and Mohamed-Noor, Jelinar and Ong, Poh-Yan and Suliman, Nurull Bahya and Lim, Ching-Wei and Zahari, Mimiwati (2022) Experience in managing glaucoma filtration surgery complications with oral doxycycline: A case series. European Journal of Ophthalmology, 32 (4). NP26-NP29. ISSN 1120-6721, DOI https://doi.org/10.1177/1120672121992953.

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Abstract

Purpose: To report the clinical profile and effectiveness of oral doxycycline as a non-invasive treatment for glaucoma filtering surgery complications. Method: Prospective case series. Results: Doxycycline is widely used in treating corneal melts, ocular surface diseases, meibomian gland disease, recurrent epithelial cell erosion, rosacea, and keratitis sicca. This prospective case series highlights the successful treatment of five patients with leaking blebs and conjunctiva erosion from glaucoma filtration surgery with the use of oral doxycycline. There was no adverse event reported in our cases. Conclusions: This study suggests that oral doxycycline may be a feasible non-surgical treatment modality due to its ability to inhibit collagenolysis, restore the Meibomian gland function, thereby stopping breakdown and promote conjunctival tissue healing.

Item Type: Article
Funders: None
Uncontrolled Keywords: Doxycycline; Glaucoma filtration surgery; Hypotony; Bleb leaks; Complication
Subjects: R Medicine > RE Ophthalmology > Ophthalmology
Divisions: Faculty of Medicine > Department of Ophthalmology
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 14 Oct 2023 06:03
Last Modified: 14 Oct 2023 06:03
URI: http://eprints.um.edu.my/id/eprint/41833

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