The impact of disease duration in persistent postural-perceptual dizziness (PPPD) on the quality of life, dizziness handicap and mental health

Teh, Carren Sui-Lin and Prepageran, Narayanan (2022) The impact of disease duration in persistent postural-perceptual dizziness (PPPD) on the quality of life, dizziness handicap and mental health. Journal of Vestibular Research-Equilibrium & Orientation, 32 (4). pp. 373-380. ISSN 0957-4271, DOI https://doi.org/10.3233/VES-210087.

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Abstract

BACKGROUND: Persistent Postural-Perceptual Dizziness (PPPD) is a chronic functional disorder which interferes with the way individuals experience their personal, social and work life. OBJECTIVE: To study the impact of disease duration in PPPD on the quality of life (QOL), dizziness handicap and mental health on the patients. METHODS: A prospective study comparing the EQ-5D for QOL, Dizziness Handicap Inventory (DHI) and DASS-21 between 27 patients with PPPD and 27 of those who have recovered from an acute vestibular event. Similar parameters between PPPD patients with symptoms less than one year and more than a year were compared. RESULTS: The PPPD patients were predominantly females and middle-aged with significantly higher DHI scores (mean 48.3 + 25.7, p = 0.00002), higher total mean scores in the DASS-21 (mean 21.6 + 13.7, p = 0.009) and poorer QOL with mean EQ-5D VAS of 67.9 + 17.3 (p < 0.00001). PPPD patients with symptoms for more than a year had significant increase in physical handicap (p = 0.041) as well as anxiety levels (p = 0.008). CONCLUSIONS: PPPD is predominantly seen in females and middle-aged which significantly reduces the QOL, increases dizziness handicap and increases depression, anxiety and stress levels. The increase in duration of illness further increases the anxiety levels and physical handicap.

Item Type: Article
Funders: None
Uncontrolled Keywords: Persistent postural-perceptual dizziness; Dizziness handicap; Quality of life; Depression; Anxiety
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RF Otorhinolaryngology
Divisions: Faculty of Medicine > Otorhinolaryngology Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 23 Oct 2023 06:38
Last Modified: 23 Oct 2023 06:38
URI: http://eprints.um.edu.my/id/eprint/41799

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