Rabiatul, A. A. R. and Rianti, Devi and Fatihhi, S. J. and Saad, Amir Putra Md and Zakaria, Zulfadzli and Yuliati, Anita and Harun, M. N. and Kadir, M. R. A. and Ochsner, Andreas and Kamarul, Tunku and Saqr, Khalid M. and Syahrom, Ardiyansyah (2022) Influence of bone marrow characteristic and trabecular bone morphology on bone remodelling process with FSI approach. Proceedings of the Institution of Mechanical Engineers Part L-Journal of Materials-Design and Applications, 236 (8). pp. 1682-1695. ISSN 1464-4207, DOI https://doi.org/10.1177/14644207221080115.
Full text not available from this repository.Abstract
While doing daily physiological activities, the trabecular bone will experience a certain amount of deformation which leads to the bone marrow movement. The movement can affect the bone remodelling process and the properties of the bone itself. The bone marrow plays a role as a hydraulic stiffening of the trabecular structure. However, previous studies analysed on trabecular bone and bone marrow separately, which is not considered as the actual condition. Thus, it is crucial to consider combine analyses of the bone marrow with the trabecular structure simultaneous. The aim of this study is to investigate the effect of bone marrow on the mechanical environment and the structure of trabecular bone during normal walking loading. Hence, this study used the Fluid-Structure Interaction (FSI) approach as a finite element method to discover the effect of bone marrow to the trabecular structure and vice versa. The findings show the shear stress value along normal walking phase was found in a range of 0.01-0.27 Pa which is sufficient to regulated cell response minimally. This study provides insight into understanding the related mechanobiological responds towards supply of nutrients onto bone cells.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Teknologi Malaysia, R.J130000.7309.4B535, Universitas Airlangga, Research Management Centre, Universiti Teknologi Malaysia |
| Uncontrolled Keywords: | Fluid Structure Interaction; Trabecular Bone; Bone Marrow; Shear Stress; Stiffness; Bone Remodelling |
| Subjects: | Q Science > QM Human anatomy |
| Divisions: | Faculty of Medicine > Orthopaedic Surgery Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 20 Nov 2023 09:24 |
| Last Modified: | 20 Nov 2023 09:24 |
| URI: | http://eprints.um.edu.my/id/eprint/41753 |
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