The metabolomics approaches based on LC-MS/MS for analysis of non-halal meats in food products: A review

Windarsih, Anjar and Rohman, Abdul and Riswanto, Florentinus Dika Octa and Dachriyanus, - and Yuliana, Nancy Dewi and Abu Bakar, Nor Kartini (2022) The metabolomics approaches based on LC-MS/MS for analysis of non-halal meats in food products: A review. Agriculture-Basel, 12 (7). ISSN 2077-0472, DOI https://doi.org/10.3390/agriculture12070984.

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Abstract

Halal meats are meats that are allowed to be consumed by Muslim societies according to Islamic law (Syariah). Due to the development of food technology, non-halal meats such as pork or canine meat are added to food products to reduce the production costs. Non-halal meats also include meats from animals which are not slaughtered according to Syariah law; therefore, the availability of a standardized analytical method capable of detecting the presence of non-halal meats with high sensitivity is very urgent. The metabolomics technique, either targeted or untargeted approaches based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) measurements is an emerging analytical method applied to the identification of non-halal meats in food products. The LC-MS/MS measurements provide an enormous metabolomics data, therefore, sophisticated data analysis tools such as chemometrics is required. Among the chemometrics techniques, exploratory data analysis for supervised and unsupervised pattern recognition, including principal component analysis (PCA), hierarchical cluster analysis (HCA), and linear-discriminant analysis (LDA), are the most-used. This review focused on the recent application of LC-MS/MS in combination with chemometrics for the detection and identification (qualitative analysis) of non-halal meats in food products. The selection criteria used for the papers in this review were studies on the application of metabolomics using LC-MS/MS and chemometrics for the halal authentication of meat products between 2005 and 2022. The results showed that potential biomarkers of non-halal meats could be found using chemometrics analysis. Therefore, it can be concluded that a combination of LC-MS/MS and chemometrics is promising for development as a standard analytical method for the analysis of non-halal meats in food products.

Item Type: Article
Funders: Universitas Gadjah Mada, 1544/UN1/DITLIT/Dit-Lit/PT.01.03/2022
Uncontrolled Keywords: Non-halal meats; Metabolomics; Chemometrics; Biomarkers; Halal authentication; LC-MS/MS
Subjects: H Social Sciences > HD Industries. Land use. Labor
Q Science > QD Chemistry
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 22 Nov 2023 07:54
Last Modified: 22 Nov 2023 07:54
URI: http://eprints.um.edu.my/id/eprint/41675

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