Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia

Turana, Yuda and Shen, Robert and Nathaniel, Michael and Chia, Yook-Chin and Li, Yan and Kario, Kazuomi (2022) Neurodegenerative diseases and blood pressure variability: A comprehensive review from HOPE Asia. Journal of Clinical Hypertension, 24 (9, SI). pp. 1204-1217. ISSN 1524-6175, DOI https://doi.org/10.1111/jch.14559.

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Abstract

Asia has an enormous number of older people and is the primary contributor to the rise in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. The therapy of many neurodegenerative diseases has not yet progressed to the point where it is possible to alter the course of the disease. Mid-life hypertension is an important predictor of later-life cognitive impairment and brain neurodegenerative conditions. These findings highlight the pivotal role of preventing and managing hypertension as a risk factor for neurodegenerative disease. Autonomic dysfunction, neuropsychiatric and sleep disturbances can arise in neurodegenerative diseases, resulting in blood pressure variability (BPV). The BPV itself can worsen the progression of the disease. In older people with neurodegenerative disease and hypertension, it is critical to consider 24-h blood pressure monitoring and personalized blood pressure therapy.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Alzheimer's disease; Hypertension; Neurodegenerative; Parkinson
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 11 Sep 2023 03:23
Last Modified: 11 Sep 2023 03:23
URI: http://eprints.um.edu.my/id/eprint/41155

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