Prevalence and risks of depression and substance use among adults living with HIV in the Asia-Pacific region

Ross, Jeremy L. and Jiamsakul, Awachana and Avihingsanon, Anchalee and Lee, Man Po and Ditangco, Rossana and Choi, Jun Yong and Rajasuriar, Reena and Gatechompol, Sivaporn and Chan, Iris and Melgar, Maria Isabel Echanis and Kim, Jung Ho and Chong, Meng Li and Sohn, Annette H. and Law, Matthew and Disabi, Subst Use Stigma Depression (2022) Prevalence and risks of depression and substance use among adults living with HIV in the Asia-Pacific region. AIDS and Behavior, 26 (12). pp. 3862-3877. ISSN 1090-7165, DOI https://doi.org/10.1007/s10461-022-03714-5.

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Abstract

Despite the mental health and substance use burden among people living with HIV (PLHIV) in the Asia-Pacific, data on their associations with HIV clinical outcomes are limited. This cross-sectional study of PLHIV at five sites assessed depression and substance use using PHQ-9 and ASSIST. Among 864 participants, 88% were male, median age was 39 years, 97% were on ART, 67% had an HIV viral load available and < 1000 copies/mL, 19% had moderate-to-severe depressive symptoms, and 80% had ever used at least one substance. Younger age, lower income, and suboptimal ART adherence were associated with moderate-to-severe depressive symptoms. Moderate-to-high risk substance use, found in 62% of users, was associated with younger age, being male, previous stressors, and suboptimal adherence. Our findings highlight the need for improved access to mental health and substance use services in HIV clinical settings.

Item Type: Article
Funders: HIV-NAT, Queen Elizabeth Hospital, TREAT Asia, amfAR, Thai Red Cross AIDS Research Centre, University Malaya Medical Centre, National Institutes of Health, National Institute of Mental Health, National Institute on Drug Abuse, National Institute on Alcohol Abuse and Alcoholism, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Allergy and Infectious Diseases, U01AI069907, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases, amfAR, The Foundation for AIDS Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Department of Health and Ageing, Australian Government, University of New South Wales
Uncontrolled Keywords: HIV; Asia; Depression; Substance use; ART adherence
Subjects: B Philosophy. Psychology. Religion > BF Psychology
H Social Sciences > HQ The family. Marriage. Woman
Divisions: Faculty of Medicine > Medicine Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 30 Nov 2023 08:54
Last Modified: 30 Nov 2023 08:54
URI: http://eprints.um.edu.my/id/eprint/40972

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