Seroepidemiology of toxoplamosis in renal patients

Nissapatorn, V.; Leong, T.H.; Lee, R.; Init, Ithoi; Ibrahim, J.; Yen, T.S. (2011) Seroepidemiology of toxoplamosis in renal patients. Southeast Asian Journal of Tropical Medicine and Public Health, 42 (2). pp. 237-247. ISSN 0125-1562

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    Toxoplasmosis is an important parasitic disease in immunosuppressed patients. This prospective study was conducted to determine the seroprevalence, associated risk factors and the incidence of clinically confirmed toxoplasmosis among renal patients at the University of Malaya Medical Center, Kuala Lumpur, Malaysia. We interviewed 247 renal patients, each of whom answered an epidemiological questionnaire, and collected blood samples for measurement of anti-Toxoplasma IgG and IgM antibodies by ELISA. Overall seroprevalence of latent toxoplasmosis was observed in 126 (51) renal patients. Race (Malays), marital status (married) and primary level of education, were all factors associated with a greater chance of Toxoplasma infection. A case of clinically confirned toxoplasmosis was diagnosed in a renal transplant recipient as a result of immunosuppression. Based on the findings obtained, this preliminary study shows a high prevalence of latent toxoplasmosis in renal patients. Risk factors may have significantly contributed to Toxoplasma acquisition in these patients. We recommend further studies be carried out to monitor for trends in toxoplasmosis among immunosuppressed patients.

    Item Type: Article
    1. Nissapatorn, V.
    2. Leong, T.H.
    3. Lee, R.
    4. Init, Ithoi
    5. Ibrahim, J.
    6. Yen, T.S.
    Journal or Publication Title: Southeast Asian Journal of Tropical Medicine and Public Health
    Additional Information: Nissapatorn, Veerartoot Leong, Teoh Hoe Lee, Rogan Init-Ithoi Ibrahim, Jamaiah Yen, Tan Si
    Uncontrolled Keywords: Hookworm; Dogs; A. ceylanicum; A. caninum; Malaysia
    Subjects: R Medicine
    Divisions: Faculty of Medicine
    Depositing User: Miss Malisa Diana
    Date Deposited: 10 Dec 2012 09:27
    Last Modified: 10 Dec 2012 09:27

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