Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia

Ngui, R.; Lim, Y.A.L.; Amir, N.F.H.; Nissapatorn, V.; Mahmud, R. (2011) Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia. American Journal of Tropical Medicine and Hygiene, 85 (4). pp. 660-666. ISSN 0002-9637

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    This study aims to evaluate the current seroprevalence of toxoplasmosis among indigenous communities in Peninsular Malaysia and relate its association with epidemiological data. Overall seroprevalence of Toxoplasma gondii was 37.0 with 31.0 immunoglobulin (Ig) G, 1.8 IgM, and 4.2 seropositivity for both anti-Toxoplasma antibodies. Multivariate analysis showed that age above 12 years (odds ratio OR = 2.70, 95% confidence interval CI = 1.75-4.04, P < 0.001), using untreated river and mountain water supplies (OR = 1.50,95% CI = 1.01-2.40, P = 0.050), and close proximity with cats (OR = 1.40, 95% CI = 1.10-1.76, P = 0.010) were factors associated with toxoplasmosis. Given the high seroprevalence of toxoplasmosis among these communities who live in poor socioeconomic conditions, a comprehensive health surveillance program and screening should be initiated among women of childbearing age and pregnant women during the antenatal period for early diagnosis and treatment. The role of domestic cats and environmental contamination with oocyst in soil and water has to be highlighted and addressed in future prevention strategies for these communities.

    Item Type: Article
    1. Ngui, R.
    2. Lim, Y.A.L.(Department of Parasitology, Faculty of Medicine University of Malaya, 50603 Kuala Lumpur, MALAYSIA)
    3. Amir, N.F.H.
    4. Nissapatorn, V.
    5. Mahmud, R.
    Journal or Publication Title: American Journal of Tropical Medicine and Hygiene
    Additional Information: Romano Ngui Lim, Yvonne A. L. Amir, Noor Farah Hani Nissapatorn, Veeranoot Mahmud, Rohela
    Uncontrolled Keywords: *Ethnic Groups Humans Malaysia/epidemiology Seroepidemiologic Studies Toxoplasmosis/*epidemiology/ethnology
    Subjects: R Medicine
    Divisions: Faculty of Medicine > School of Medicine
    Depositing User: Ms Johana Johari
    Date Deposited: 07 Nov 2012 11:46
    Last Modified: 07 Nov 2012 11:46

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