Nasaruddin, Nur Husnina and Ahmad, Shahrul Nizam and Sirat, Siti Syaida and Tan, Kong Wai and Zakaria, Nurul Aili and Nazam, Siti Sarra Mohamad and Abd Rahman, Nor Mas Mira and Mohd Yusof, Nor Saadah and Bahron, Hadariah (2022) Synthesis, structural characterization, hirshfeld surface analysis, and antibacterial study of Pd(II) and Ni(II) schiff base complexes derived from aliphatic diamine. ACS Omega, 7 (47). pp. 42809-42818. ISSN 2470-1343, DOI https://doi.org/10.1021/acsomega.2c04688.
Full text not available from this repository.Abstract
A Schiff base bearing two methyl substituents, namely, 6,6 `-((1E,1 ` E)-((2,2-dimethylpropane-1,3-diyl) bis-( azanylylidene)) bis (m ethanylylidene ) ) bi s ( 2-m ethylp henol) H2AD1Me] was synthesized and characterized through physico-chemical and spectroscopic analyses. Then, the Schiff base was complexed with Pd(II) and Ni(II) to form Pd(AD1Me)] and Ni(AD1Me)], respectively. Both metal complexes were successfully obtained and characterized through several analyses, viz., melting point, elemental analysis, molar conductivity, magnetic suscepti-bility, FTIR, 1H NMR, UV-vis, and single crystal X-ray diffraction. A quantitative analysis of the intermolecular interactions in the crystal structures has been performed using Hirshfeld surface analysis. Both metal complexes were crystallized in a monoclinic crystal system with the space group of P21/c. Additionally, the deprotonated phenolic oxygen atom (O1/O2) and azomethine nitrogen atom (N1/N2) of the ligand chelate the Pd(II) and Ni(II) ions, forming a slightly distorted square-planar complex containing three six-membered rings encircling the metal core with dsp2 hybridization. The shift of nu(C=N) to a higher frequency in FTIR by 26-28 cm-1 indicated that the complexation to Pd(II) and Ni(II) through the azomethine N was established. It was further supported through the shifting of the azomethine proton signal to higher or lower chemical shifts with Delta delta = 0.43-1.15 ppm in 1H NMR. In addition, the shifting of the n-pi*(C=N) band in UV-vis spectra with Delta lambda = 24-40 nm indicated the involvement of azomethine nitrogen in the complexation. All the compounds showed no significant antibacterial activity against three bacterial strains, namely, Staphylococcus aureus subsp. aureus Rosenbach (ATCC 6538), Streptococcus mutans Clarke (ATCC 700,610), and Proteus vulgaris (ATCC 6380), as the percent growth inhibition calculated was less than 90%.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Higher Education & Scientific Research (MHESR), Malaysia and Universiti Teknologi MARA (UiTM) (Grant No: 600-RMC/GIP 5/3(137/2021)) |
| Uncontrolled Keywords: | Crystal-structure; Ligands |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 23 Nov 2023 01:59 |
| Last Modified: | 23 Nov 2023 01:59 |
| URI: | http://eprints.um.edu.my/id/eprint/40344 |
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