Mustapa, Mohammad Adam and Guswenrivo, Ikhsan and Zuhrotun, Ade and Khairul Ikram, Nur Kusaira and Muchtaridi, Muchtaridi (2022) Anti-breast cancer activity of essential oil: A systematic review. Applied Sciences-Basel, 12 (24). ISSN 2076-3417, DOI https://doi.org/10.3390/app122412738.
Full text not available from this repository.Abstract
Breast cancer is the second highest cancer-related death worldwide. The treatment for breast cancer is via chemotherapy; however, occurrences of multidrug resistance, unselective targets, and physicochemical problems suggest that chemotherapy treatment is ineffective. Therefore, there is a need to find better alternatives. Essential oil is a plant secondary metabolite having promising bioactivities and pharmacological effects, including anti-breast cancer capabilities. This review intends to discuss and summarize the effect of essential oils on anti-breast cancer from published journals using keywords in PubMed, Scopus, and Google Scholar databases. Our findings reveal that the compositions of essential oils, mainly terpenoids, have excellent anti-breast cancer pharmacological effects with an IC50 value of 0.195 mu g/mL. Hence, essential oils have potential as anti-breast cancer drugs candidates with the highest efficacy and the fewest side effects.
| Item Type: | Article |
|---|---|
| Funders: | Rector Universitas Padjadjaran, Indonesia 2203/UN6.3.1/PT.00/2022 |
| Uncontrolled Keywords: | Breast cancer; Essential oils; Terpenoids |
| Subjects: | Q Science > QD Chemistry R Medicine > RC Internal medicine R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Faculty of Science > Institute of Biological Sciences |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 19 Oct 2023 04:41 |
| Last Modified: | 23 Oct 2023 08:02 |
| URI: | http://eprints.um.edu.my/id/eprint/40299 |
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