Exploring the potential of stem cell-based therapy for aesthetic and plastic surgery

Tran, Dang-Khoa and Phuong, Thuy Nguyen Thi and Bui, Nhat-Le and Singh, Vijai and Looi, Qi Hao and Koh, Benson and Zaman, Ungku Mohd Shahrin B. Mohd and Foo, Jhi Biau and Wu, Chia-Ching and Show, Pau Loke and Chu, Dinh-Toi (2023) Exploring the potential of stem cell-based therapy for aesthetic and plastic surgery. IEEE Reviews in Biomedical Engineering, 16. pp. 386-402. ISSN 1937-3333, DOI https://doi.org/10.1109/RBME.2021.3134994.

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Abstract

Over the last decade, stem cell-associated therapies are widely used because of their potential in self-renewable and multipotent differentiation ability. Stem cells have become more attractive for aesthetic uses and plastic surgery, including scar reduction, breast augmentation, facial contouring, hand rejuvenation, and anti-aging. The current preclinical and clinical studies of stem cells on aesthetic uses also showed promising outcomes. Adipose-derived stem cells are commonly used for fat grafting that demonstrated scar improvement, anti-aging, skin rejuvenation properties, etc. While stem cell-based products have yet to receive approval from the FDA for aesthetic medicine and plastic surgery. Moving forward, the review on the efficacy and potential of stem cell-based therapy for aesthetic and plastic surgery is limited. In the present review, we discuss the current status and recent advances of using stem cells for aesthetic and plastic surgery. The potential of cell-free therapy and tissue engineering in this field is also highlighted. The clinical applications, advantages, and limitations are also discussed. This review also provides further works that need to be investigated to widely apply stem cells in the clinic, especially in aesthetic and plastic contexts.

Item Type: Article
Funders: None
Uncontrolled Keywords: Stem cells; Self-renewable; Clinical applications; Aesthetic medicine; Grafting; Plastic surgery
Subjects: R Medicine > RD Surgery
Divisions: Faculty of Medicine > Orthopaedic Surgery Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 21 Nov 2023 09:43
Last Modified: 21 Nov 2023 09:43
URI: http://eprints.um.edu.my/id/eprint/40227

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