Effect of rocuronium compared with succinylcholine on intraocular pressure during rapid sequence induction of anaesthesia.

Chiu, C.L. and Jaais, F. and Wang, C.Y. (1999) Effect of rocuronium compared with succinylcholine on intraocular pressure during rapid sequence induction of anaesthesia. BJA: British Journal of Anaesthesia, 82 (5). pp. 757-60. ISSN 0007-0912

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/10536557

Abstract

We have compared the effect of rocuronium and succinylcholine on intraocular pressure (IOP) during rapid sequence induction of anaesthesia using propofol and fentanyl, in a randomized double-blind study. We studied 30 adult patients, allocated to one of two groups. Anaesthesia was induced with fentanyl 2 micrograms kg-1 and propofol until loss of verbal response. This was followed by succinylcholine 1.5 mg kg-1 (group S; n = 15) or rocuronium 0.9 mg kg-1 (group R; n = 15). Laryngoscopy was performed 60 s later. IOP, mean arterial pressure (MAP) and heart rate (HR) were measured before induction, immediately before intubation and every minute after intubation for 5 min. A Keeler Pulsair air impulse tonometer was used to measure IOP and the mean of two readings obtained in the right eye at each measurement time was recorded. Intubating conditions were evaluated according to a simple scoring system. IOP in the succinylcholine group was significantly greater than that in the rocuronium group (mean 21.6 (SEM 1.4) mm Hg vs 13.3 (1.4) mm Hg; P < 0.001). Intubating conditions were equally good in both groups. We conclude that with rapid sequence induction of anaesthesia using propofol and fentanyl, rocuronium did not cause as great an increase in IOP as succinylcholine and may be an alternative in open eye injury cases.

Item Type: Article
Additional Information: Department of Anaesthesia, University of Malaya
Uncontrolled Keywords: Adolescent; Anesthesia, Intravenous;
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 05 Mar 2011 01:36
Last Modified: 14 Jul 2017 07:24
URI: http://eprints.um.edu.my/id/eprint/401

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