Virucidal activity of Virkon S on human enterovirus

Chan, Y.F.; AbuBakar, S. (2005) Virucidal activity of Virkon S on human enterovirus. The Medical journal of Malaysia, 60 (2). p. 246. ISSN 0300-5283

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Abstract

The efficacy of Virkon S, a commercial disinfectant as a virucidal spray against human enterovirus 71 (HEV71), the causative agent of the fatal form of hand, foot and mouth disease was examined. At least one log10 reduction of HEV71 titer was achieved when one spray of Virkon (1 or 2) with ten minutes of contact time was applied. The infectivity was completely lost when four sprays of 1 or 2 Virkon were applied, suggesting that at least four sprays of 1 Virkon to the surface bound HEV71 was necessary to completely inactivate the virus. These findings suggest that Virkon S at the proper concentration is suitable to be used as an effective and easy to use disinfectant against HEV71.

Item Type: Article
Journal or Publication Title: The Medical journal of Malaysia
Additional Information: Department of Medical Microbiology, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords: Administration, Topical Disinfectants/administration & dosage/*therapeutic use Enterovirus/*classification/*drug effects Enterovirus Infections/*drug therapy/virology Humans Peroxides/administration & dosage/*therapeutic use Sulfuric Acids/administration & dosage/*therapeutic use Treatment Outcome
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Johana Johari
Date Deposited: 12 Nov 2012 09:30
Last Modified: 20 Oct 2014 13:39
URI: http://eprints.um.edu.my/id/eprint/3956

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