Gauhar, Vineet and Chew, Ben Hall and Traxer, Olivier and Tailly, Thomas and Emiliani, Esteban and Inoue, Takaaki and Tiong, Heng Chin and Chai, Chu Ann and Lakmichi, Mohamed Amine and Tanidir, Yiloren and Hamri, Saeed Bin and Desai, Devang and Biligere, Sarvajit and Shrestha, Anil and Soebhali, Boyke and Keat, William Ong Lay and Mohan, Vaddi Chandra and Bhatia, Tanuj Paul and Singh, Abhishek and Saleem, Mohamed and Gorelov, Dmitry and Gadzhiev, Nariman and Pietropaolo, Amelia and Galosi, Andrea Benedetto and Ragoori, Deepak and Teoh, Jeremy Yuen-Chun and Somani, Bhaskar Kumar and Castellani, Daniele (2023) Indications, preferences, global practice patterns and outcomes in retrograde intrarenal surgery (RIRS) for renal stones in adults: results from a multicenter database of 6669 patients of the global FLEXible ureteroscopy Outcomes Registry (FLEXOR). World Journal of Urology, 41 (2). pp. 567-574. ISSN 0724-4983, DOI https://doi.org/10.1007/s00345-022-04257-z.
Full text not available from this repository.Abstract
PurposeTo collect a multicentric database on behalf of TOWER research group to assess practice patterns and outcomes of retrograde intrarenal surgery (RIRS) for kidney stones. MethodsInclusion criteria: age & GE; 18 years, normal renal/calyceal system anatomy, calculi of any size, number, and position. Study period: January 2018 and August 2021. Stone-free status: absence of fragments > 2 mm, assessed post procedure according to the local protocol (KUB X-Ray and/or ultrasound or non-contrast CT scan). ResultsTwenty centers from fifteen countries enrolled 6669 patients. There were 4407 (66.2%) men. Mean age was 49.3 & PLUSMN; 15.59 years. Pain was the most frequent symptom indication for intervention (62.6%). 679 (10.2%) patients underwent RIRS for an incidental finding of stones. 2732 (41.0%) patients had multiple stones. Mean stone size was 10.04 & PLUSMN; 6.84 mm. A reusable flexible ureteroscope was used in 4803 (72.0%) procedures. A sheath-less RIRS was performed in 454 (6.8%) cases. Holmium:YAG laser was used in 4878 (73.1%) cases. A combination of dusting and fragmentation was the most common lithotripsy mode performed (64.3%). Mean operation time was 62.40 & PLUSMN; 17.76 min. 119 (1.8%) patients had an intraoperative injury of the ureter due to UAS insertion. Mean postoperative stay was 3.62 & PLUSMN; 3.47 days. At least one postoperative complication occurred in 535 (8.0%) patients. Sepsis requiring intensive care admission occurred in 84 (1.3%) patients. Residual fragments were detected in 1445 (21.7%) patients. Among the latter, 744 (51.5%) patients required a further intervention. ConclusionOur database contributes real-world data to support to a better understanding of modern RIRS practice and outcomes.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Kidney calculi; Flexible ureteroscopy; Retrograde intrarenal surgery; Lithotripsy; Laser |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 05 Nov 2025 01:19 |
| Last Modified: | 05 Nov 2025 01:19 |
| URI: | http://eprints.um.edu.my/id/eprint/39206 |
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