A transparent fuzzy rule-based clinical decision support system for heart disease diagnosis

Lahsasna, A. and Ainon, R.N. and Zainuddin, R. and Bulgiba, A.M. (2012) A transparent fuzzy rule-based clinical decision support system for heart disease diagnosis. Knowledge Technology, 295 (2). pp. 62-71.

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Heart disease (HD) is a serious disease and its diagnosis at early stage remains a challenging task. A well-designed clinical decision support system (CDSS), however, that provides accurate and understandable decisions would effectively help the physician in making an early and appropriate diagnosis. In this study, a CDSS for HD diagnosis is proposed based on a genetic-fuzzy approach that considers both the transparency and accuracy of the system. Multi-objective genetic algorithm is applied to search for a small number of transparent fuzzy rules with high classification accuracy. The final fuzzy rules are formatted to be structured, informative and readable decisions that can be easily checked and understood by the physician. Furthermore, an Ensemble Classifier Strategy (ECS) is presented in order to enhance the diagnosis ability of our CDSS by supporting its decision, in the uncertain cases, by other well-known classifiers. The results show that the proposed method is able to offer humanly understandable rules with performance comparable to other benchmark classification methods.

Item Type: Article
Additional Information: Department of Social and Preventive Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords: Heart disease; fuzzy system; transparency; medical diagnosis
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Haslinda Lahuddin
Date Deposited: 07 Nov 2012 03:22
Last Modified: 07 Nov 2012 03:22
URI: http://eprints.um.edu.my/id/eprint/3919

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