Mohamad Naguib, Adrina and Apparoo, Yasaaswini and Xiong, Chuan and Phan, Chia Wei (2023) Maitake medicinal mushroom, Grifola frondosa (Agaricomycetes), and its neurotrophic properties: A mini-review. International Journal of Medicinal Mushrooms, 25 (2). pp. 11-22. ISSN 1521-9437, DOI https://doi.org/10.1615/IntJMedMushrooms.2022046849.
Full text not available from this repository.Abstract
Neurodegeneration is one of the most common manifestations in an aging population. The occurrence of oxidative stress and neuroinflammation are the main contributors to the phenomenon. Neurologic conditions such as Alzheimer's disease (AD) and Parkinson's disease (PD) are challenging to treat due to their irreversible manner as well as the lack of effective treatment. Grifola frondosa (Dicks.: Fr.) S.F. Gray, or maitake mushroom, is believed to be a potential choice as a therapeutic agent for neurodegenerative diseases. G. frondosa is known to be a functional food that has a wide variety of medicinal purposes. Thus, this review emphasizes the neuroprotective effects and the chemical composition of G. frondosa. Various studies have described that G. frondosa can protect and proliferate neuronal cells through neurogenesis, antioxidative, anti-inflammatory, and anti-beta-amyloid activities. The mechanism of action behind these therapeutic findings in various in vitro and in vivo models has also been intensively studied. In this mini review, we also summarized the chemical composition of G. frondosa to provide a better understanding of the presence of nutritional compounds in G. frondosa.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Higher Education, Malaysia, FP016-2019A, FRGS/1/2019/ SKK09/UM/02/2 |
| Uncontrolled Keywords: | Grifola frondosa; Neurodegeneration; Antioxidative; Anti-inflammatory; Anti-beta-amyloid; Tau protein; Medicinal mushrooms |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmaceutical Life Sciences |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 29 Nov 2023 02:19 |
| Last Modified: | 29 Nov 2023 02:19 |
| URI: | http://eprints.um.edu.my/id/eprint/39060 |
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