Isolated cervical lymph node sarcoidosis: A diagnostic challenge of a case report

Lim, Chee Chean and Ghauth, Sakina and Liew, Yew Toong and bin Abu Bakar, Mohd Zukiflee and Narayanan, Prepageran A. L. (2023) Isolated cervical lymph node sarcoidosis: A diagnostic challenge of a case report. European Archives of Oto-Rhino-Laryngology, 280 (2). pp. 925-927. ISSN 09374477, DOI https://doi.org/10.1007/s00405-022-07808-7.

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Abstract

Background:Sarcoidosis is a granulomatous disorder involving multi-systemic organs. Patients invariably have lung involvement but some may have extrapulmonary disease. Rarely, cervical lymphadenopathy is the only sign without mediastinal or pulmonary abnormalities. Case presentation:We report a Malay male who complained of neck swelling exclusively. On imaging, multiple enlarged cervical lymph nodes deep to the sternocleidomastoid muscle were seen. An excision biopsy revealed non-caseating granulomas with epithelioid macrophages. Extensive investigations led to the diagnosis of isolated cervical lymph node sarcoidosis. Conclusions:Sarcoidosis can present as cervical lymphadenopathy alone, without mediastinal or lung disease. The presence of epithelioid granulomas on histopathology warrants the exclusion of other granulomatous diseases. Isolated cervical lymph node sarcoidosis is only diagnosed in the presence of consistent clinical and radiological findings. In this case, close monitoring for systemic sarcoidosis is important as it can manifest later in life.

Item Type: Article
Funders: None
Uncontrolled Keywords: Granulomatous disease; Cervical lymphadenopathy; Sarcoidosis; Lymph node excision; Biopsy
Subjects: R Medicine > RF Otorhinolaryngology
Divisions: Faculty of Medicine > Otorhinolaryngology Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 24 Nov 2024 03:12
Last Modified: 24 Nov 2024 03:12
URI: http://eprints.um.edu.my/id/eprint/38906

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