A review on taste masked multiparticulate dosage forms for paediatric

AL-Japairai, Khater and Almurisi, Samah Hamed and Doolaanea, Abd Almonem and Mahmood, Syed and Alheibshy, Fawaz and Alobaida, Ahmed and Abdul-Halim, Nadiya and Chatterjee, Bappaditya (2023) A review on taste masked multiparticulate dosage forms for paediatric. International Journal of Pharmaceutics, 632. ISSN 0378-5173, DOI https://doi.org/10.1016/j.ijpharm.2022.122571.

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Abstract

Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous contributing components such as swallowability, palatability (taste, flavour, texture, and mouthfeel), appearance, ease of administration, and patient characteristics. Multiparticulate as a dosage form is a platform technology for overcoming paediatrics' incapacity to swallow monolithic dosage forms, masking many medications' inherent nasty taste, and over-coming the obstacles of manufacturing a commercially taste masked dosage form. This review will discuss the considerations that must be taken into account to prepare taste masked multiparticulate dosage forms in the best way for paediatric use.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Paediatric; Unpleasant drug; Taste masking; Multiparticulate system
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy
Faculty of Pharmacy > Department of Pharmaceutical Technology
Depositing User: Ms Zaharah Ramly
Date Deposited: 04 Nov 2024 02:22
Last Modified: 04 Nov 2024 02:22
URI: http://eprints.um.edu.my/id/eprint/38854

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