Gender differences in the associations between knee pain and urinary incontinence in older adults: Cross-sectional analysis from the Malaysian Elders Longitudinal Research Study (MELoR)

Mat, Sumaiyah and Jaafar, Mohamad Hasif and Abdul Razack, Azad Hassan Abdul and Lim, Jasmine and Ong, Teng Aik and Khong, Su-Yen and Kamaruzzaman, Shahrul Bahyah and Chin, Ai-Vyrn and Abbas, Azlina Amir and Chan, Chee Ken and Hairi, Noran Naqiah and Othman, Sajaratulnisah and Tan, Maw Pin and Investigators, MELoR (2023) Gender differences in the associations between knee pain and urinary incontinence in older adults: Cross-sectional analysis from the Malaysian Elders Longitudinal Research Study (MELoR). Neurourology and Urodynamics, 42 (3). pp. 641-649. ISSN 0733-2467, DOI https://doi.org/10.1002/nau.25136.

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Abstract

IntroductionThe common assumption that urinary incontinence occurs in osteoarthritis (OA) due to poor mobility is supported by limited evidence. The influence of gender in such associations is also yet to be elucidated. ObjectiveThis study, therefore, identified any potential associations between knee OA symptoms and urinary incontinence and further explore sex differences in the associations. DesignCross-sectional study. SettingUniversity Hospital. ParticipantsThis was a cross-sectional study from a longitudinal research study comprising 1221 community-dwelling older persons (57% women), mean age (SD) 68.95 (7.49) years. Main Outcome Measure(s)Presence of urinary incontinence: mixed, stress and urge symptoms. Physical performance and C-reactive protein levels were also assessed. ResultsTwo hundred and seventy-seven (22.83%) individuals reported the presence of urinary incontinence: mixed (41.5%), stress (30%), and urge (28.5%) symptoms. In an unadjusted analysis, stratified by gender, the association between knee pain and urinary incontinence was only present in women with mixed symptoms. After further adjustment of demographics differences and body mass index, the association between knee pain with any urinary incontinence and mixed symptoms remained significant with the odds ratios (95% confidence interval): 1.48 (1.02-2.15) and 1.73 (1.06-2.83), respectively. This relationship was attenuated after further adjustment for waist circumference and impaired lower limb mobility. ConclusionOur study refutes previous assumptions that urinary incontinence in individuals with OA is attributed to impaired mobility alone, but introduces the role of abdominal obesity in this relationship, particularly in women. Future studies should assess the temporal relationship between body fat distribution and OA with urinary incontinence.

Item Type: Article
Funders: Ministry of Higher Education Malaysia Long Term Research Grant Scheme, (LR005-2019) LRGS/1/2019/UM//1/1
Uncontrolled Keywords: Aged; Central obesity; Knee; Osteoarthritis; Urinary Incontinence
Subjects: H Social Sciences > HQ The family. Marriage. Woman
H Social Sciences > HV Social pathology. Social and public welfare
Divisions: Faculty of Medicine > Medicine Department
Faculty of Medicine > Surgery Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 28 Nov 2023 08:31
Last Modified: 28 Nov 2023 08:31
URI: http://eprints.um.edu.my/id/eprint/38650

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