Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide

Cahyanto, Arief and Liemidia, Michella and Karlina, Elin and Zakaria, Myrna Nurlatifah and Shariff, Khairul Anuar and Sukotjo, Cortino and El-Ghannam, Ahmed (2023) Bioactive carbonate apatite Cement with enhanced compressive strength via incorporation of silica calcium phosphate composites and calcium hydroxide. Materials, 16 (5). ISSN 1996-1944, DOI https://doi.org/10.3390/ma16052071.

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Abstract

Carbonate apatite (CO(3)Ap) is a bioceramic material with excellent properties for bone and dentin regeneration. To enhance its mechanical strength and bioactivity, silica calcium phosphate composites (Si-CaP) and calcium hydroxide (Ca(OH)(2)) were added to CO(3)Ap cement. The aim of this study was to investigate the effect of Si-CaP and Ca(OH)(2) on the mechanical properties in terms of the compressive strength and biological characteristics of CO(3)Ap cement, specifically the formation of an apatite layer and the exchange of Ca, P, and Si elements. Five groups were prepared by mixing CO(3)Ap powder consisting of dicalcium phosphate anhydrous and vaterite powder added by varying ratios of Si-CaP and Ca(OH)(2) and 0.2 mol/L Na2HPO4 as a liquid. All groups underwent compressive strength testing, and the group with the highest strength was evaluated for bioactivity by soaking it in simulated body fluid (SBF) for one, seven, 14, and 21 days. The group that added 3% Si-CaP and 7% Ca(OH)(2) had the highest compressive strength among the groups. SEM analysis revealed the formation of needle-like apatite crystals from the first day of SBF soaking, and EDS analysis indicated an increase in Ca, P, and Si elements. XRD and FTIR analyses confirmed the presence of apatite. This combination of additives improved the compressive strength and showed the good bioactivity performance of CO(3)Ap cement, making it a potential biomaterial for bone and dental engineering applications.

Item Type: Article
Funders: Directorate of Higher Education Republic of Indonesia and Padjadjaran University, Indonesia (1207/UN6.3.1/PT.00/2021)
Uncontrolled Keywords: Compressive strength; Bioactivity; Carbonate apatite; Silica calcium phosphate composite; Calcium hydroxide; SBF
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry
Depositing User: Ms Zaharah Ramly
Date Deposited: 06 Jul 2023 02:46
Last Modified: 06 Jul 2023 02:46
URI: http://eprints.um.edu.my/id/eprint/38485

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