Research progress on extraction and analytical methods for saxitoxin and its congeners

Ishak, Siti Munirah and Yahaya, Noorfatimah and Loh, Saw Hong and Kamaruzaman, Sazlinda and Zain, Nur Nadhirah Mohamad and Waras, Maisarah Nasution and Abdullah, Wan Nazwanie Wan and Miskam, Mazidatulakmam and Raoov, Muggundha and Aziz, Noorizan Abd and Hassan, Yahaya (2023) Research progress on extraction and analytical methods for saxitoxin and its congeners. Chromatographia, 86 (5). pp. 349-373. ISSN 0009-5893, DOI https://doi.org/10.1007/s10337-023-04251-6.

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Abstract

Saxitoxin is a potent neurotoxin commonly found in shellfish, produced by dinoflagellate and cyanobacterial blooms in seawater or fresh water. This review dissects the conventional liquid-liquid extraction (LLE) and solid-phase extraction (SPE) and the emerging microscale sample preparation method, followed by their achievements in the preconcentration of saxitoxin-group toxins from different matrices. Despite the tedious and multi-step procedures, LLE and SPE remain the most applied techniques in detecting saxitoxin due to their high sensitivity and selectivity. Nevertheless, microscale sample preparation offers potential as a green technique, especially in the development of advanced adsorbents for better sensitivity.

Item Type: Article
Funders: Ministry of Higher Education Malaysia [FRGS/1/2021/STG04/USM/02/4, 203.CIPPT.6711973]
Uncontrolled Keywords: Saxitoxin; Sample preparation; Paralytic shellfish toxins; Foods; Environmental; Biological
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Ms Zaharah Ramly
Date Deposited: 12 Jun 2024 00:27
Last Modified: 12 Jun 2024 00:27
URI: http://eprints.um.edu.my/id/eprint/38301

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