Cheah, Min Hui and Lai, Pauline Siew Mei and Khor, Hui Min and Ratnasingam, Jeyakantha and Chandrasekaran, C. Sankara Kumar and Singh, Simmrat and Zakaria, Mohd Idzwan and Ong, Terence (2023) Fragility fracture care gap at a tertiary teaching hospital in Malaysia. Archives of Osteoporosis, 18 (1). ISSN 1862-3522, DOI https://doi.org/10.1007/s11657-023-01256-4.
Full text not available from this repository.Abstract
Fracture begets fracture, pharmacological treatment is needed to prevent secondary fractures. This study found that there was a fragility fracture care gap where both bone health investigations and treatment initiation rates were low. Strategies such as Fracture Liaison Service is needed to address the care gap.PurposeThis study aimed to investigate the clinical burden and secondary fracture prevention of fragility fractures at a tertiary teaching hospital in Malaysia.MethodsElectronic medical records of all patients admitted with fragility fractures between 1 January 2017-31 December 2018 were reviewed. Patients < 50 years old, with non-fragility fractures, restricted access to medical records, transferred to another hospital or who passed away during admission were excluded. Descriptive statistics were used to summarise patients' characteristics, frequency of fragility fractures, and secondary fracture prevention details. Binomial logistic regression was performed to analyse predictive factors for post-fracture bone health assessments and treatment initiation.Results1030 patients female (767/1030, 74.5%)] presented with 1071 fractures hip fractures (378/1071, 35.3%)]. 170/993 (17.1%) patients were initiated on anti-osteoporosis medications (AOMs) and 148/984 (15.0%) had bone mineral density (BMD) performed within 1-year post-fracture. Less than half (42.4%) of the patients remained on treatment at 1-year post-fracture. Older patients 65-74 years old: odds ratio (OR) = 2.18, 95%CI 1.05-4.52, p = 0.04; >= 75 years: OR = 3.06, 95%CI 1.54-6.07, p < 0.01], hip fractures (OR = 1.95, 95%CI 1.23-3.11, p < 0.01), Chinese ethnicity (OR = 1.90, 95%CI 1.07-3.35, p = 0.03),previously diagnosed with osteoporosis (OR = 2.65, 95%CI:1.32-5.31, p < 0.01) and a BMD test performed (OR = 12.48, 95%CI 8.04-19.37, p < 0.01) were found to have higher AOM initiation. Patients with past diagnosis of osteoporosis (OR = 4.45, 95%CI 2.25-8.81, p < 0.01) and initiated on AOM (OR = 11.34, 95%CI 7.57-16.97, p < 0.01) had a higher likelihood to undergo BMD testing.ConclusionThe AOM initiation and BMD testing rates were low. There is a need to address the fragility fracture care gap with strategies such as Fracture Liaison Service.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Osteoporosis; Malaysia; Fragility fractures; Bone density; Osteoporosis treatment |
| Subjects: | R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine > Medicine Department Faculty of Medicine > Primary Care Medicine Department |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 27 Nov 2023 07:27 |
| Last Modified: | 03 Dec 2023 01:37 |
| URI: | http://eprints.um.edu.my/id/eprint/38253 |
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