Genetic polymorphisms of interleukin-4 third intron region in the Malaysian patients with systemic lupus erythematosus

Chua, K.H.; Pin, K.B.; Yen, T.S.; Hoong, L.L. (2008) Genetic polymorphisms of interleukin-4 third intron region in the Malaysian patients with systemic lupus erythematosus. Journal of Medical Sciences, 8 (4). pp. 437-442. ISSN 1682-4474

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    Abstract

    In this study, we analysed the genetic polymorphisms present in the third intron region of Interleukin-4 gene in Malaysian patients with Systemic Lupus Erythematosus. Overall, the RP I and II alleles were found evenly distributed in both the SLE patients and control individuals. There was no significant association observed in the distribution of allelic and genotypic frequencies between SLE patients and healthy controls. The result obtained is similar to a previous study carried out on SLE Chinese patients in Taiwan.

    Item Type: Article
    Creators:
    1. Chua, K.H.(Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA)
    2. Pin, K.B.
    3. Yen, T.S.
    4. Hoong, L.L.
    Journal or Publication Title: Journal of Medical Sciences
    Additional Information: Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
    Uncontrolled Keywords: Interleukin-4 ; systemic lupus erythematosus ; genetic polymorphisms ; third intron ; variable number of tandem repeat
    Subjects: R Medicine
    Divisions: Faculty of Medicine
    Depositing User: Ms azrahani halim
    Date Deposited: 01 Nov 2012 12:25
    Last Modified: 01 Nov 2012 12:25
    URI: http://eprints.um.edu.my/id/eprint/3815

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