Validity of the FACT-H&N (v 4.0) among Malaysian oral cancer patients

Doss, Jennifer Geraldine and Thomson, W. Murray and Drummond, Bernadette Kathleen and Raja-Latifah, Raja Jallaludin (2011) Validity of the FACT-H&N (v 4.0) among Malaysian oral cancer patients. Oral Oncology, 47 (7). pp. 648-652. ISSN 1368-8375

[img] PDF
Restricted to Registered users only

Download (161kB) | Request a copy
Official URL:


To assess the cross-sectional construct validity of the Malay-translated and cross-culturally adapted FACT-H&N (v 4.0) for discriminative use in a sample of Malaysian oral cancer patients. A cross-sectional study of adults newly diagnosed with oral cancer. HRQOL data were collected using the FACT-H&N (v 4.0), a global question and a supplementary set of eight questions (‘MAQ’) obtained earlier in pilot work. Of the 76 participants (61.8% female; 23.7% younger than 50), most (96.1%) had oral squamous cell carcinoma; two-thirds were in Stages III or IV. At baseline, patients’ mean FACT summary (FACT-G, FACT-H&N, FACT-H&N TOI, and FHNSI) and subscale (pwb, swb, ewb, fwb, and hnsc) scores were towards the higher end of the range. Equal proportions (36.8%) rated their overall HRQOL as ‘good’ or ‘average’; fewer than one-quarter rated it as ‘poor’, and only two as ‘very good’. All six FACT summary and most subscales had moderate-to-good internal consistency. For all summary scales, those with ‘very poor/poor’ self-rated HRQOL differed significantly from the ‘good/very good’ group. All FACT summary scales correlated strongly (r > 0.75). Summary scales showed convergent validity (r > 0.90) but little discriminant validity. The discriminant validity of the FHNSI improved with the addition of the MAQ. The FACT-H&N summary scales and most subscales demonstrated acceptable cross-sectional construct validity, reliability and discriminative ability, and thus appear appropriate for further use among Malaysian oral cancer patients.

Item Type: Article
Additional Information: ISI Document Delivery No.: 782QL Times Cited: 0 Cited Reference Count: 16 Doss, J. G. Thomson, W. M. Drummond, B. K. Latifah, R. J. Raja University of Otago; two University of MalayaFS337/2007C, F0379/2005B We thank the oral and maxillofacial surgeons and their respective data collectors from the seven participating hospitals in this study, as well as all patients who so generously participated in this study. This study was supported by the University of Otago Dato Dr. Sulaiman Daud Jubilee Award and two University of Malaya Grants (FS337/2007C and F0379/2005B). Elsevier science bv Amsterdam
Uncontrolled Keywords: Validity; Head and neck cancer; Oral cancer; Oral cavity; Cross-cultural; Quality of life; Psychosocial factors
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dept of Community Dentistry
Depositing User: Mr Ahmad Azwan Azman
Date Deposited: 23 Oct 2012 03:56
Last Modified: 13 Nov 2019 02:37

Actions (login required)

View Item View Item


Downloads per month over past year