Rahim, Z.H.A.; Khan, H.B. (2006) Comparative studies on the effect of crude aqueous (CA) and solvent (CM) extracts of clove on the cariogenic properties of Streptococcus mutans. European Journal of Oral Sciences, 48 (3). pp. 117-123. ISSN 0909-883
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Abstract
A study was conducted to compare the efficiency of crude aqueous (CA) and solvent extracts (CM) of clove on the caries-inducing properties of Streptococcus mutans. The cariogenic properties investigated included the cell adhesion, cell-surface hydrophobicity and glucan synthesis activities of S. mutans. There was a significant difference between the effect of the CA and CM extracts on the adhesion of S. mutans (P < 0.05) within a concentration range of 5-15 mg/ml, the CM extract demonstrating a slightly higher inhibitory effect. However, the effect of the CM extract on the cell-surface hydrophobicity of S. mutans was weaker than that of the CA extract. The two extracts were found to reduce the synthesis of water-insoluble glucan (WIG) by almost 50 at a concentration as low as 0.5 mg/ml and the CM extract exhibited a significantly higher inhibitory effect than the CA extract (P < 0.05). The present findings indicate that both the CA and CM extracts exert inhibitory effects on the cariogenic properties of S. mutans and that the CA extract is as equally effective as the CM extract.
| Item Type: | Article |
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| Journal or Publication Title: | European Journal of Oral Sciences |
| Additional Information: | Cited By (since 1996): 12 Export Date: 10 September 2012 Source: Scopus PubMed ID: 17023743 Language of Original Document: English Correspondence Address: Rahim, Z.H.email: zubaidar@um.edu.my Chemicals/CAS: glucan, 9012-72-0, 9037-91-6; glucosyltransferase, 9031-48-5; Cariostatic Agents; Glucans; Glucosyltransferases, 2.4.1.-; Plant Extracts |
| Uncontrolled Keywords: | Anticaries agent glucan glucosyltransferase plant extract article bacterium adherence biosynthesis chemistry comparative study drug antagonism drug effect Eugenia hydrophobicity metabolism Streptococcus mutans Bacterial Adhesion Cariostatic Agents Chemistry, Pharmaceutical Glucans Glucosyltransferases Plant Extracts |
| Subjects: | R Medicine > RK Dentistry |
| Divisions: | Faculty of Dentistry > Dept of Oral Biology |
| Depositing User: | Mr Ahmad Azwan Azman |
| Date Deposited: | 08 Oct 2012 12:22 |
| Last Modified: | 13 Mar 2013 17:00 |
| URI: | http://eprints.um.edu.my/id/eprint/3749 |
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