Genotype-Phenotype diversity of Beta-Thalassemia in Malaysia: treatment options and emerging therapies

Elizabeth, G.; Ann, T.J.A.M. (2010) Genotype-Phenotype diversity of Beta-Thalassemia in Malaysia: treatment options and emerging therapies. Medical Journal of Malaysia, 65 (4). ISSN 0300-5283

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    Abstract

    The haemoglobinopathies and thalassemias represent the most common inherited monogenic disorders in the world. Beta-thalassaemia major is an ongoing public health problem in Malaysia. Prior to 2004, the country had no national policy for screening and registry for thalassemia. In the absence of a national audit, the true figure of the extent of thalassemia in the Malaysian population was largely presumptive from micro-mapping studies from various research workers in the country. The estimated carrier rate for beta-thalassemia in Malaysia is 3.5-4. There were 4768 transfusion dependent thalassemia major patients as of May 2010 (Data from National Thalassemia Registry).

    Item Type: Article
    Creators:
    1. Elizabeth, G.
    2. Ann, T.J.A.M.(Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA)
    Journal or Publication Title: Medical Journal of Malaysia
    Additional Information: Department of Molecular Medicine, Faculty of Medicine, Unieversity of Malaya, 50603, Kuala Lumpur
    Uncontrolled Keywords: Genotype-phenotype thalassemia Malaysia treatment options
    Subjects: R Medicine
    Divisions: Faculty of Medicine
    Depositing User: Ms Haslinda Lahuddin
    Date Deposited: 02 Oct 2012 10:07
    Last Modified: 02 Oct 2012 10:07
    URI: http://eprints.um.edu.my/id/eprint/3710

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