Survival of surgically-treated patients with squamous cell carcinoma of the buccal mucosa
Jailani, M.A.; Rahman, Z.A.A. (2007) Survival of surgically-treated patients with squamous cell carcinoma of the buccal mucosa. Asian Journal of Oral and Maxillofacial Surgery, 19 (1). pp. 34-37. ISSN 0915-6992
Objective: The aim of this study was to establish clinical outcomes from surgical treatment of squamous cell carcinoma of the buccal mucosa in terms of survival rates and disease-free period and their relationships with other variables. Patients and Methods: This survival study of squamous cell carcinoma of the buccal mucosa was done at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Malaya. The case notes of 55 patients were reviewed retrospectively and the demographic data analysed. Survival rates were determined using the Kaplan-Meier method and the distribution of each variable in the survival studies was analysed by the log rank test. Results: The subjects ranged in age from 42 to 78 years (mean, 61.6 years) and the female-to-male ratio was 6:1. The overall 5-year cumulative survival probability was 49.7. Survival was strongly influenced by tumour stage, neck node involvement, and tumour grade. Conclusion: The treatment outcome of this study is comparable with studies conducted elsewhere. The results emphasise the importance of early detection and intervention in maximising survival in this setting. Â© 2007 Asian Association of Oral and Maxillofacial Surgeons.
|Item Type: ||Article|
- Jailani, M.A.
- Rahman, Z.A.A.
|Journal or Publication Title: ||Asian Journal of Oral and Maxillofacial Surgery|
|Additional Information: ||Export Date: 4 September 2012 Source: Scopus CODEN: AJMSF Language of Original Document: English Correspondence Address: Rahman, Z.A.A.; Department of Oral and Maxillofacial Surgery, Dental Faculty, University of Malaya, Kuala Lumpur 50603, Malaysia; email: firstname.lastname@example.org References: Warnakulasuriya, S., Global trends in the epidemiology of oral cancer; the current position (2005) Oral Oncol, 1 (SUPPL.), p. 27; Bloom, N.D., Spiro, R.H., Carcinoma of cheek mucosa. A retrospective analysis (1980) Am J Surg, 140, pp. 556-559; Strome, S.E., To, W., Strawderman, M., Gersten, K., Devaney, K.O., Bradford, C.R., Squamous cell carcinoma of the buccal mucosa (1999) Otolaryngol Head Neck Surg, 120, pp. 375-379; Neville, B.W., Day, T.A., Oral cancer and precancerous lesions (2002) CA Cancer J Clin, 52, pp. 195-215; Jones, A.S., Houghton, D.J., Beasley, N.J., Husband, D.J., Improved survival in patients with head and neck cancer in the 1990s (1998) Clin Otolaryngol Allied Sci, 23, pp. 319-325; Shingaki, S., Takada, M., Sasai, K., Bibi, R., Kobayashi, T., Nomura, T., Impact of lymph node metastasis on the pattern of failure and survival in oral carcinomas (2003) Am J Surg, 185, pp. 278-284; Inagi, K., Takahashi, H., Okamaoto, M., Nakayama, M., Makoshi, T., Nagai, H., Treatment effects in patients with squamous cell carcinoma of the oral cavity (2002) Acta Otolaryngol Suppl, 547, pp. 25-29; Ildstad, S.T., Bigelow, M.E., Remensnyder, J.P., Clinical behavior and results of current therapeutic modalities for squamous cell carcinoma of the buccal mucosa (1985) Surg Gynecol Obstet, 160, pp. 254-258; Urist, M.M., O'Brien, C.J., Soong, S.J., Visscher, D.W., Maddox, W.A., Squamous cell carcinoma of buccal mucosa: Analysis of prognostic factors (1987) Am J Surg, 154, pp. 411-414; Woolgar, J.A., Scott, J., Vaughan, E.D., Brown, J.S., West, C.R., Rogers, S., Survival, metastasis and recurrence of oral cancer in relation to pathological features (1995) Ann R Coll Surg Engl, 77, pp. 325-331; Majoufre, C., Faucher, A., Laroche, C., De Bonfils, C., Siberchicot, F., Renaud-Salis, J.L., Supraomohyoid neck dissection in cancer of the oral cavity (1999) Am J Surg, 178, pp. 73-77; Woolgar, J.A., Beirne, J.C., Vaughan, E.D., Lewis-Jones, H.G., Scott, J., Brown, J.S., Correlation of histopathologic findings with clinical and radiologic assessments of cervical lymph-node metastases in oral cancer (1995) Int J Oral Maxillofac Surg, 24, pp. 30-37; Anneroth, G., Hansen, L.S., Silverman, S., Malignancy grading in oral squamous cell carcinoma. I. Squamous cell carcinoma of the tongue and floor of mouth: Histologic grading in the clinical evaluation (1986) J Oral Pathol, 15, pp. 162-168|
|Uncontrolled Keywords: ||Mouth neoplasms Risk factors Squamous cell carcinoma Surgery Survival adult aged article cancer survival cheek mucosa controlled study female follow up human major clinical study male mouth carcinoma treatment outcome tumor recurrence tumor volume|
|Subjects: ||R Medicine > RK Dentistry|
|Divisions: ||Faculty of Dentistry > Dept of Oral & Maxillofacial Surgery|
|Depositing User: ||Mr Ahmad Azwan Azman|
|Date Deposited: ||24 Sep 2012 09:52|
|Last Modified: ||24 Sep 2012 09:52|
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