Mousavi, Seyyed Mojtaba and Low, Foo Wah and Hashemi, Seyyed Alireza and Samsudin, Nurul Asma and Shakeri, Mohammad and Yusoff, Yulisa and Rahsepar, Mansoor and Lai, Chin Wei and Babapoor, Aziz and Soroshnia, Sadaf and Goh, Su Mei and Tiong, Sieh Kiong and Amin, Nowshad (2020) Development of hydrophobic reduced graphene oxide as a new efficient approach for photochemotherapy. RSC Advances, 10 (22). pp. 12851-12863. ISSN 2046-2069, DOI https://doi.org/10.1039/d0ra00186d.
Full text not available from this repository.Abstract
Nowadays, chemotherapy is one of the crucial and common therapies in the world. So far, it has been revealed to be highly promising, yet patients suffer from the consequences of severe negative medical dosages. In order to overcome these issues, the enhancement of photothermal chemotherapy with reduced graphene oxide (rGO) as a photothermal agent (PTA) is widely utilised in current medical technologies. This is due to its high near-infrared region (NIR) response, in vitro or in vivo organism biocompatibility, low risk of side effects, and effective positive results. Moreover, rGO not only has the ability to ensure that selective cancer cells have a higher mortality rate but can also improve the growth rate of recovering tissues that are untouched by necrosis and apoptosis. These two pathways are specific diverse modalities of cell death that are distinguished by cell membrane disruption and deoxyribonucleic acid (DNA) disintegration of the membrane via phosphatidylserine exposure in the absence of cell membrane damage. Therefore, this review aimed to demonstrate the recent achievements in the modification of rGO nanoparticles as a PTA as well as present a new approach for performing photochemotherapy in the clinical setting.
| Item Type: | Article |
|---|---|
| Funders: | Impact-Oriented Interdisciplinary Research Grant [IIRG018A-2019], Global Collaborative Programme-SATU Joint Research Scheme [ST012-2019], BOLD2025 Grant [10436494/B/2019008], Internal Research Grant Opex under Universiti Tenaga Nasional Sdn. Bhd., Malaysia [RJO10517919/iRMC/Publication] |
| Uncontrolled Keywords: | photothermal cancer-therapynear-infrared absorbency photothermal cancer-therapynear-infrared absorbency photothermal cancer-therapynear-infrared absorbency Photothermal cancer-therapy; Near-infrared absorbency |
| Subjects: | T Technology > TP Chemical technology |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 04 Oct 2023 06:52 |
| Last Modified: | 04 Oct 2023 06:52 |
| URI: | http://eprints.um.edu.my/id/eprint/36801 |
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