Delayed onset cerebral vasculitis from chronic Schistosoma mansoni infection in Myanmar: A case report

Nyein, Aye Myat and Sann, Aye Aye and Aye, Nu Nu and Tan, Chong Tin (2020) Delayed onset cerebral vasculitis from chronic Schistosoma mansoni infection in Myanmar: A case report. Neurology Asia, 25 (2). pp. 203-206. ISSN 1823-6138,

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Abstract

Neurosehistosomiasis is an infection of the central nervous system caused by Schistosoma species and constitute a severe manifestation of the disease. Schistosoma japonicum is well-latown cause of cerebral schistosomiasis and Schistosoma mansoni for spinal schistosomiasis. Although neuroschistosomiasis is not rare, reports on cerebral vasculitis associated with Schistosoma mansoni infection is scarce. With regards to schistosomiasis in Asia, most of the published literature has been on Schistosoma japonicum and the prevalence of Schistosoma mansoni in Asia is not well established. We report here a 54-year-old Rakhine woman with history of diabetes mellitus for more than ten years presenting with three recurrent stroke occurring over 2 months, twelve months after returning to Yangon from Rakhine, an endemic area for Schistosoma niansoni infection. Cerebral NfRA revealed beaded appearance along left ACA and segmental narrowing beyond terminal ICA both sides, and contrast enhancement was noted at left frontal lobe with restricted diffusion on MRI brain. Serum serology testing for Schistosoma mansoni infection was positive. With oral praziquantel and high dose corticosteroid, aphasia and swallowing improved. This is the first report of delayed onset cerebral vasculitis associated with chronic Schistosoma mansoni infection in Asia.

Item Type: Article
Funders: None
Uncontrolled Keywords: Asia; Stroke; Cerebral vasculitis; Schistosoma mansoni; Corticosteroid; Praziquantel
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Medicine > Neurosurgery Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 04 Nov 2024 02:13
Last Modified: 04 Nov 2024 02:13
URI: http://eprints.um.edu.my/id/eprint/36667

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