Jeger, Raban V. and Eccleshall, Simon and Wan Ahmad, Wan Azman and Ge, Junbo and Poerner, Tudor C. and Shin, Eun-Seok and Alfonso, Fernando and Latib, Azeem and Ong, Paul J. and Rissanen, Tuomas T. and Saucedo, Jorge and Scheller, Bruno and Kleber, Franz X. (2020) Drug-coated balloons for coronary artery disease third report of the international DCB consensus group. JACC-Cardiovascular Interventions, 13 (12). pp. 1391-1402.
Full text not available from this repository.Abstract
Although drug-eluting stents are still the default interventional treatment of coronary artery disease, drug-coated balloons (DCBs) represent a novel alternative therapeutic strategy in certain anatomic conditions. The effect of DCBs is based on the fast and homogenous transfer of antiproliferative drugs into the vessel wall during single balloon inflation by means of a lipophilic matrix without the use of permanent implants. Although their use is established for in-stent restenosis of both bare-metal and drug-eluting stents, recent randomized clinical data demonstrate a good efficacy and safety profile in de novo small-vessel disease and high bleeding risk. In addition, there are other emerging indications (e.g., bifurcation lesions, large-vessel disease, diabetes mellitus, acute coronary syndromes). Because the interaction among the different delivery balloon designs, doses, formulations, and release kinetics of the drugs used is important, there seems to be no “class effect” of DCBs. On the basis of the amount of recently published data, the International DCB Consensus Group provides this update of previous recommendations summarizing the historical background, technical considerations such as choice of device and implantation technique, possible indications, and future perspectives. © 2020 The Authors
| Item Type: | Article |
|---|---|
| Funders: | Charité University Hospital, Medtronic, Boston Scientific Corporation |
| Uncontrolled Keywords: | Angioplasty, Balloon, Coronary; Cardiac Catheters; Cardiovascular Agents; Clinical Decision-Making; Consensus; Coronary Angiography; Coronary Artery Disease; Drug-Eluting Stents; Equipment Design; Humans; Risk Factors; Treatment Outcome |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > School of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 13 Aug 2024 03:03 |
| Last Modified: | 13 Aug 2024 03:03 |
| URI: | http://eprints.um.edu.my/id/eprint/36606 |
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