Endocrine-Disrupting Chemicals Role in Drug Abuser: A Review Study

Wiraagni, Idha Arfianti and Mohd, Mustafa Ali and Abdul Rashid, Rusdi and Mohamad Haron, Didi Erwandi (2020) Endocrine-Disrupting Chemicals Role in Drug Abuser: A Review Study. International Journal Of Medical Toxicology And Forensic Medicine, 10 (4). ISSN 22518762, DOI https://doi.org/10.32598/ijmtfm.v10i4.26324.

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Abstract

Endocrine-disrupting Chemicals (EDCs) are exogenous chemicals that influence many aspects of natural hormone actions. Bisphenol is used in the industry, for increasing the thickness and durability of materials in certain plastics and resins. Paraben is used as preservatives in many pharmaceuticals, cosmetics, and some food products. EDCs can increase estrogen levels inside the body, and estrogen itself can increase the monoamine effect (dopamine, serotonin), neuronal excitability, neuropeptide transmitter mechanism, and drug metabolism. In drug abusers, this effect can develop greater craving behavior, addiction, and relapse.

Item Type: Article
Funders: None
Uncontrolled Keywords: EDCs; Bisphenol; Paraben
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Zaharah Ramly
Date Deposited: 30 Dec 2023 13:52
Last Modified: 30 Dec 2023 13:52
URI: http://eprints.um.edu.my/id/eprint/36470

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