Diagnostic approaches and contribution of next-generation sequencing technologies in genomic investigation ofVibrio parahaemolyticusthat caused acute hepatopancreatic necrosis disease (AHPND)

Yu, Lean Huat and Teh, Cindy Shuan Ju and Yap, Kien Pong and Thong, Kwai Lin (2020) Diagnostic approaches and contribution of next-generation sequencing technologies in genomic investigation ofVibrio parahaemolyticusthat caused acute hepatopancreatic necrosis disease (AHPND). Aquaculture International, 28 (6). pp. 2547-2559. ISSN 0967-6120, DOI https://doi.org/10.1007/s10499-020-00610-4.

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Abstract

A unique strain ofVibrio parahaemolyticus(designated as VPAHPND) causes acute hepatopancreatic necrosis disease (AHPND), a deadly bacterial disease associated with mass mortality in cultured shrimps since 2009. AHPND is responsible for severe economic losses worldwide, causing multimillion-dollar loss annually. Because of the rapid and high mortality rates in shrimps, substantial research has been carried out to develop rapid detection techniques. Also, recent technological advances such as the next-generation sequencing (NGS) have made it possible to elucidate relevant information about a pathogen in a single assay. This review summarizes the current research pertaining to VPAHPND, focusing on diagnosis and contribution of NGS technologies in the genomic studies of AHPND.

Item Type: Article
Funders: University of Malaya, UM GRANT - Frontier Research Grant [Grant No: UM.0000149/HGA.GV, FG029-17AFR]
Uncontrolled Keywords: Acute hepatopancreatic necrosis disease; Vibrio parahaemolyticus; Diagnostics; Next-generation sequencing
Subjects: Q Science > Q Science (General)
S Agriculture > SH Aquaculture. Fisheries. Angling
Divisions: Faculty of Medicine > Medical Microbiology Department
Faculty of Science > Institute of Biological Sciences
Nanotechnology & Catalysis Research Centre
Depositing User: Ms Zaharah Ramly
Date Deposited: 27 Nov 2024 00:45
Last Modified: 27 Nov 2024 00:45
URI: http://eprints.um.edu.my/id/eprint/36391

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