Goh, S. H. and Khor, K. H. and Ismail, R. and Rani, Megat Abdul P. A. and Mohd Mohidin, Taznim Begam and Bahaman, A. R. and Khairani-Bejo, S. and Radzi, R. and Alashraf, A. R. and Sabri, A. R. and Lau, S. F. (2020) Detection and distribution of anti-leptospiral antibody among dogs and their handlers. TROPICAL BIOMEDICINE, 37 (4). pp. 1074-1082. ISSN 01275720, DOI https://doi.org/10.47665/TB.37.4.1074.
Full text not available from this repository.Abstract
The incidence of leptospirosis seems to be on the rise and could be an alarming indirect indication of a global re-emergence. It is a potential public health threat when dogs are speculated to be involved in the transmission of leptospirosis through possible subclinical harbouring of Leptospira spp. and subsequent shedding into the environment. This study aimed to detect anti-leptospiral antibodies among dogs and their handlers using the microscopic agglutination test (MAT). Blood samples from 266 apparently healthy dogs and 194 dog handlers were collected at four working dog organisations and four dog shelters. Serum samples were tested using MAT against 20 leptospiral serovars with a cut-off titre >= 1:100 (dog) and >= 1:50 (dog handlers). Seventy dogs (70/266; 26.3%) were seropositive mainly against serovars Icterohaemorrhagiae, Ballum, Bataviae and Javanica (titres ranged: 1:100-1:800). Sixty-seven dog handlers (67/194; 34.5%) were seropositive mainly against serovars Grippotyphosa, Icterohaemorrhagiae and Malaysia (titres ranged: 1:50-1:200). Dogs were seropositive due to exposure, vaccination or active infection. Seropositive dog handlers could indicate exposure or active infection. This shows the potential of dogs in maintaining and spreading the infection in Malaysia. Due to the occupational risk as a result of frequent contact with dogs and exposure to contaminated environments, dog handlers should be made aware of the presence of this zoonotic disease.
| Item Type: | Article |
|---|---|
| Funders: | Faculty of Veterinary Medicine, Universiti Putra Malaysia |
| Uncontrolled Keywords: | antibody; anti-leptospiral |
| Subjects: | Q Science > QL Zoology |
| Divisions: | Faculty of Science > Institute of Biological Sciences |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 28 Dec 2023 07:01 |
| Last Modified: | 28 Dec 2023 07:01 |
| URI: | http://eprints.um.edu.my/id/eprint/36211 |
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