Balasekaran, Narendra and Soelar, Shahrul Aiman and Anbarasen, Lalita and Cham, Chun Yoong and Rajandram, Retnagowri and Sia, Sheau Fung (2021) Vasospasm and delayed cerebral ischaemia in patients with spontaneous subarachnoid haemorrhage (aneurysmal and pretruncal non-aneurysmal): A centre’s perspective. Medical Journal of Malaysia, 76 (1). pp. 17-23. ISSN 0300-5283,
Full text not available from this repository.Abstract
Spontaneous subarachnoid haemorrhage (SAH) is a significant cause of stroke and associated with high morbidity and mortality. One substantial complication of SAH is cerebral vasospasm (CV) and delayed cerebral ischemia (DCI). This study aimed to define the clinical profile in patients with SAH, CV and DCI secondary to spontaneous SAH (aneurysmal and pretruncal non-aneurysmal). Materials and Methods: We analysed 122 consecutive patients with spontaneous SAH following intracranial aneurysmal and non-aneurysmal information (including patients’ pattern characterisation and their possible risk factor association to pre-operative clinical decision and long-term clinical outcome) was documented and analysed. Results: The main clinical presentations for spontaneous SAH following ruptured intracranial aneurysm and non-aneurysm were headache (77) and nausea/vomiting (62.3). The most common sites for SAH following ruptured intracranial aneurysm rupture were the anterior and posterior communicating arteries (57.5). Hypertension was the most common cause for SAH at 64.8. It was found 26.2 (n=32) out of the 122 patients developed CV and DCI. The mean day of vasospasm was 6.0 ± 2.8 (range: 1-14 days) Age, length of stay, nausea/vomiting and visual field defect were significantly associated (p<0.05) with vasospasm. Mortality rate was also higher in the CV group compared to the group without CV in both at discharge and at 6 months; 281 versus 278 per 1000 and 312 vs 300 per 1000, respectively. Conclusion: CV and DCI have a significant incidence among local patients with spontaneous SAH following an intracranial aneurysmal and non-aneurysmal rupture and it is associated with substantial morbidity. Prevention, effective monitoring, and early detection are keys to successful management. Regional investigation using a multicentre cohort to analyse mortality and survival rates may aid in improving national resource management of these patients. © 2021, Malaysian Medical Association. All rights reserved.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Cerebral vasospasm;Delayed cerebral ischaemia;Malaysia;Outcome;Spontaneous subarachnoid haemorrhage |
| Subjects: | R Medicine R Medicine > RD Surgery |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 03 Nov 2022 03:42 |
| Last Modified: | 03 Nov 2022 03:42 |
| URI: | http://eprints.um.edu.my/id/eprint/36039 |
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