Rajah, Rathika and Yee, Lim Kuan and Hau, Ng Boon and Soo, Chun Ian (2021) The utility of n-terminal pro-brain natriuretic peptide as an adjunct diagnostic tool for acute heart failure in acute dyspneic patients coming to the emergency department: A retrospective review of our early experience. Malaysian Journal of Medical Sciences, 28 (4). pp. 146-152. ISSN 1394-195X, DOI https://doi.org/10.21315/mjms2021.28.4.15.
Full text not available from this repository.Abstract
Acute dyspnea is one of the prevalent reasons for admission to the emergency department. The use of N-terminal pro-B-type natriuretic peptide (NT-proBNP) as an adjunct for assessing acute dyspnea is not a common practice in many public hospitals in Malaysia. This retrospective review is part of our clinical audit to determine the utility of NT-proBNP as an adjunct to non-standardised clinical evaluation in identifying acute heart failure (HF) in patients with persistent dyspnea (24 h) post-admission. In this cohort of 30 patients with acute dyspnea, NT-proBNP was positive in zo patients (87%) with acute HF. Three patients (13%) who were treated for septic shock recorded a NT-proBNP false-positive. NT-proBNP demonstrated an overall sensitivity of 90%, a specificity of 70%, a positive predictive value of 85.7% and a negative predictive value of 77.8% in identifying acute HF. These results reinforce that age-stratified NT-proBNP cut-off values are useful for ruling-in or -out acute HF. Thus, NT-proBNP should be considered a crucial point of care, testing to deafer the conundrum of acute dyspneic patients.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Acute heart failure; N-terminal pro-brain natriuretic peptide |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 01 Sep 2022 07:47 |
| Last Modified: | 01 Sep 2022 07:47 |
| URI: | http://eprints.um.edu.my/id/eprint/35186 |
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