Jairoun, Ammar Abdulrahman and Al-Hemyari, Sabaa Saleh and Shahwan, Moyad and Ibrahim, Baharudin and Hassali, Mohamed Azmi and Zyoud, Sa'ed H. (2021) Risk assessment of over-the-counter cannabinoid-based cosmetics: Legal and regulatory issues governing the safety of cannabinoid-based cosmetics in the UAE. Cosmetics, 8 (3). ISSN 2079-9284, DOI https://doi.org/10.3390/cosmetics8030057.
Full text not available from this repository.Abstract
The lack of scientific evidence of the safety and efficacy of over-the-counter topical cannabinoid-based cosmetics remains a concern. The current study attempted to assess the quality of cannabinoid-based cosmetic products available on the UAE market. In particular, the study attempted to quantify the presence of undeclared tetrahydrocannabinol, specifically delta-9-tetrahydrocannabinol (THC) and delta-9-tetrahydrocannabinolic acid (THCA), in these products. Methods: A total of 18 cannabinoid-based cosmetics were collected and analysed in this study. GC-MS analysis was used to determine the presence of total undeclared tetrahydrocannabinol. Results: The estimate for the average tetrahydrocannabinol content was 0.011% with a 95% CI (0.004-0.019). Leave-on cosmetics products are more likely to contain total tetrahydrocannabinol compared to rinse-off cosmetics (p = 0.041). Although there was no statistically significant difference in the total tetrahydrocannabinol according to cosmetic category, there was a tendency towards higher tetrahydrocannabinol content in the hand care products, baby products, and body care preparations. Conclusion: The current study reveals the need for producers of cannabinoid-based cosmetic products to issue quality certificates for each batch produced to inform users of the tested levels of tetrahydrocannabinol.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Tetrahydrocannabinol;Over the counter;Cannabis sativa;Cannabidiol |
| Subjects: | R Medicine R Medicine > RA Public aspects of medicine R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 08 Sep 2022 01:56 |
| Last Modified: | 08 Sep 2022 01:56 |
| URI: | http://eprints.um.edu.my/id/eprint/35008 |
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