Yap, Phui-Chyng and MatRahim, Nor-Aziyah and AbuBakar, Sazaly and Lee, Hai Yen (2021) Antilisterial potential of lactic acid bacteria in eliminating listeria monocytogenes in host and ready-to-eat food application. Microbiology Research, 12 (1). pp. 234-257. ISSN 2036-7481, DOI https://doi.org/10.3390/microbiolres12010017.
Full text not available from this repository.Abstract
Listeriosis is a severe food borne disease with a mortality rate of up to 30% caused by pathogenic Listeria monocytogenes via the production of several virulence factors including listeriolysin O (LLO), transcriptional activator (PrfA), actin (Act), internalin (Int), etc. It is a foodborne disease predominantly causing infections through consumption of contaminated food and is often associated with ready-to-eat food (RTE) and dairy products. Common medication for listeriosis such as antibiotics might cause an eagle effect and antibiotic resistance if it is overused. Therefore, exploration of the use of lactic acid bacteria (LAB) with probiotic characteristics and multiple antimicrobial properties is increasingly getting attention for their capability to treat listeriosis, vaccine development, and hurdle technologies. The antilisterial gene, a gene coding to produce antimicrobial peptide (AMP), one of the inhibitory substances found in LAB, is one of the potential key factors in listeriosis treatment, coupled with the vast array of functions and strategies; this review summarizes the various strategies by LAB against L. monocytogenes and the prospect in development of a `generally regarded as safe' LAB for treatment of listeriosis.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Education, Malaysia [FRGS049-2018A], Bantuan Kecil Penyelidik Universiti Malaya [BK056-2016], Higher Institution Centre for Excellence (HICoE) program [MO002-2019] |
| Subjects: | Q Science > QR Microbiology |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 26 May 2022 08:02 |
| Last Modified: | 26 May 2022 08:02 |
| URI: | http://eprints.um.edu.my/id/eprint/34897 |
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