COVID-19 infection among older people admitted to hospital: A cross-sectional analysis

Thiam, Chiann Ni and Hasmukharay, Kejal and Lim, Wan Chieh and Ng, Chai Chen and Pang, Gordon Hwa Mang and Abdullah, Aimy and Saedon, Nor Izzati and Khor, Hui Min and Ong, Terence (2021) COVID-19 infection among older people admitted to hospital: A cross-sectional analysis. Geriatrics, 6 (1). ISSN 2308-3417, DOI https://doi.org/10.3390/geriatrics6010025.

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Abstract

(1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (>= 60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020-25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection.

Item Type: Article
Funders: UNSPECIFIED
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Medicine Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 27 May 2022 03:13
Last Modified: 27 May 2022 03:13
URI: http://eprints.um.edu.my/id/eprint/34855

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