Optimising the scan delay for arterial phase imaging of the liver using the bolus tracking technique.

Chan, R. and Kumar, G. and Abdullah, B. and Ng, K.H. and Vijayananthan, A. and Mohd Nor, H. and Liew, Y. (2011) Optimising the scan delay for arterial phase imaging of the liver using the bolus tracking technique. Biomedical Imaging and Intervention Journal, 7 (2). ISSN 1823-5530, DOI PMID: 22287986.

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Abstract

OBJECTIVE: To optimize the delay time before the initiation of arterial phase scan in the detection of focal liver lesions in contrast enhanced 5 phase liver CT using the bolus tracking technique. PATIENTS AND METHODS: Delay - the interval between threshold enhancement of 100 hounsfield unit (HU) in the abdominal aorta and commencement of the first arterial phase scan. Using a 16 slice CT scanner, a plain CT of the liver was done followed by an intravenous bolus of 120 ml nonionic iodinated contrast media (370 mg I/ml) at the rate of 4 mL/s. The second phase scan started immediately after the first phase scan. The portal venous and delay phases were obtained at a fixed delay of 60 s and 90 s from the beginning of contrast injection. Contrast enhancement index (CEI) and subjective visual conspicuity scores for each lesion were compared among the three groups. RESULTS: 84 lesions (11 hepatocellular carcinomas, 17 hemangiomas, 39 other hypervascular lesions and 45 cysts) were evaluated. CEI for hepatocellular carcinomas appears to be higher during the first arterial phase in the 6 seconds delay group. No significant difference in CEI and mean conspicuity scores among the three groups for hemangioma, other hypervascular lesions and cysts. CONCLUSION: The conspicuity of hepatocellular carcinomas appeared better during the early arterial phase using a bolus tracking technique with a scan delay of 6 seconds from the 100 HU threshold in the abdominal aorta.

Item Type:	Article
Funders:	UNSPECIFIED
Additional Information:	Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia ----> Corresponding author. Address: Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. E-mail: ruohshyuan@gmail.com (Ruoh Shyuan Chan).
Uncontrolled Keywords:	Arterial phase imaging of the liver, Bolus tracking technique
Subjects:	R Medicine
Divisions:	Faculty of Medicine
Depositing User:	Mr. Faizal Hamzah
Date Deposited:	03 Jul 2012 02:21
Last Modified:	14 Jul 2017 08:27
URI:	http://eprints.um.edu.my/id/eprint/3457

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