Prevalence study of epilepsy in Malaysia

Fong, Si-Lei and Lim, Kheng-Seang and Tan, LeeAnn and Zainuddin, Nabilah Hanis and Ho, Jun-Hui and Chia, Zhi-Jien and Choo, Wan-Yuen and Puvanarajah, Santhi Datuk and Chinnasami, Suganthi and Tee, Sow-Kuan and Raymond, Azman Ali and Law, Wan-Chung and Tan, Chong-Tin (2021) Prevalence study of epilepsy in Malaysia. Epilepsy Research, 170. ISSN 0920-1211, DOI https://doi.org/10.1016/j.eplepsyres.2021.106551.

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Abstract

The lifetime prevalence of epilepsy varies greatly from 1.5-14.0 per 1000 persons among the Asian countries. We aim to study the prevalence of epilepsy in Malaysia to have a better insight into the burden of disease in the country. Methods: A population-based door-to-door survey was carried out throughout the country, using questionnaire for brief screening in ascertainment of epilepsy, using a questionnaire and its validated multilingual versions. Respondents who were screened positive underwent second-stage diagnostic phone interview by neurologists/research assistants. Results: A total 16, 686 respondents participated in the survey and 646 (3.8 %) respondents were screened positive during the first stage interview. A total of 185 consented for second stage diagnostic interview and 118 (63.8 %) respondents were contacted successfully for the second stage diagnostic phone interview, of which 17 (14.4 %) respondents were diagnosed to have epilepsy. An additional 68 (57.6 %) respondents had febrile seizures only. After applying a weighting factor to each respondent to adjust for non-response and for the varying probabilities of selection, the adjusted lifetime epilepsy prevalence was 7.8 in 1000 population, and the adjusted prevalence for active epilepsy was 4.2 in 1000 population in Malaysia. Conclusion: The prevalence of lifetime epilepsy in Malaysia is 7.8 per 1000 persons.

Item Type: Article
Funders: University of Malaya Specialist Centre (UMSC) CA.R.E. grant[PV 056-2018], Institute for Public Health (IPH) of Malaysia
Uncontrolled Keywords: Prevalence;Epilepsy;Malaysia
Subjects: R Medicine
R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Medicine
Depositing User: Ms Zaharah Ramly
Date Deposited: 14 Sep 2022 04:51
Last Modified: 14 Sep 2022 04:51
URI: http://eprints.um.edu.my/id/eprint/34504

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