Coenzyme, cofactor and prosthetic group : ambiguous biochemical jargon

Hashim, Onn Haji and Adnan, N.A. (1994) Coenzyme, cofactor and prosthetic group : ambiguous biochemical jargon. Biochemical Education, 22 (2). pp. 93-94. ISSN 1879-1468, DOI https://doi.org/10.1016/0307-4412(94)90088-4.

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Abstract

For enzymes which require non-protein components to be functionally active, it is generally accepted that the term holoenzyme refers to the complete catalytic entity which consists of a protein part known as the apoenzyme and a non-protein constituent. The terms used for the functionally required non-protein constituents however, are ambiguous and differ from one commonly used biochemistry textbook to another. In certain textbooks, any associative non-protein factor required for the enzymatic function is termed coenzyme. The coenzyme may eitherbe a prosthetic group — the tightly bound coenzyme, or a cofactor — the loosely bound small organic or inorganic molecule.

Item Type:	Article
Funders:	UNSPECIFIED
Additional Information:	Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords:	Molecular Medicine
Subjects:	R Medicine
Divisions:	Faculty of Medicine
Depositing User:	Ms Haslinda Lahuddin
Date Deposited:	11 Jul 2012 01:48
Last Modified:	24 Oct 2019 08:15
URI:	http://eprints.um.edu.my/id/eprint/3450

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