Van, Minh Huynh and Anh, Tien Hoang and Thuc, Sinh Cao and Chi, Thang Doan and Chen, Chen-Huan and Tay, Jam Chin and Siddique, Saulat and Wang, Tzung-Dau and Sogunuru, Guru Prasad and Chia, Yook-Chin and Kario, Kazuomi (2021) Assessment of preferred methods to measure insulin resistance in Asian patients with hypertension. The Journal of Clinical Hypertension, 23 (3, SI). pp. 529-537. ISSN 1524-6175, DOI https://doi.org/10.1111/jch.14155.
Full text not available from this repository.Abstract
Insulin resistance (IR), a metabolic risk factor, is linked to the pathogenetic mechanism of primary hypertension. Detecting IR in the patients with hypertension will help to predict and stratify the added cardiovascular risk, institute appropriate IR management, and manage hypertension optimally. There are many methods for assessing IR, each with distinct advantages and disadvantages. The euglycemic insulin clamp and intravenous glucose tolerance test, gold standards for measuring IR, are used in research but not in clinical practice. Homeostatic model assessment (HOMA-IR), a method for assessing beta-cell function and IR, is frequently applied presently, particularly in Asia. Besides, the triglyceride-glucose index (TyG) first published by South American authors showed a good correlation with the insulin clamp technique and HOMA-IR index. This simple, convenient, and low-cost TyG index is of research interest in many countries in Asia and can be used to screen for IR in the Asian hypertensive community.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Asia patients; Hypertension; Insulin resistance |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine > Mental healin |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 31 May 2022 08:34 |
| Last Modified: | 31 May 2022 08:34 |
| URI: | http://eprints.um.edu.my/id/eprint/34450 |
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