Wahab, Nurul W. A. and Guad, Rhanye M. and Subramaniyan, Vetriselvan and Fareez, Ismail M. and Choy, Ker W. and Bonam, Srinivasa R. and Selvaraju, Chandrasekaran and Sim, Maw Shin and Gopinath, Subash C. B. and Wu, Yuan S. (2021) Human exfoliated deciduous teeth stem cells: Features and therapeutic effects on neurogenerative and hepatobiliary-pancreatic diseases. Current Stem Cell Research & Therapy, 16 (5). pp. 563-576. ISSN 1574-888X, DOI https://doi.org/10.2174/1574888X15999200918105623.
Full text not available from this repository.Abstract
Stem cells can multiply into more cells with similar types in an undifferentiated form and differentiate into other types of cells. The great success and key essence of stem cell technology is the isolation of high-quality Mesenchymal Stem Cells (MSCs) with high potency, either with multipotent or pluripotent property. In this line, Stem cells from Human Exfoliated Deciduous teeth (SHEDs) are highly proliferative stem cells from dental pulp and have multipoint differentiation capacity. These cells play a pivotal role in regenerative medicine, such as cell repair associated with neurodegenerative, hepatobiliary, and pancreatic diseases. In addition, stem cell therapy has been widely used to regulate immune response and repair of tissue lesions. This overview captured the differential biological characteristics, and the potential role of stem cell technology and paid special attention to human welfare SHEDs in eliminating the above-mentioned diseases. This review provides further insights into stem cell technology by expanding the therapeutic potential of SHEDs in tissue engineering and cell organ repairs.
| Item Type: | Article |
|---|---|
| Funders: | Funding agency Grant number Fundamental Research Grant Scheme [FRGS/1/2019/SKK10/MAH-SA/03/1], MAHSA University [RP165-05/19] |
| Uncontrolled Keywords: | Totipotency; Pluripotent; Human exfoliated deciduous teeth; SHEDs; Neurodegenerative disease; Retinal degenera-tion; Liver diseases; Diabetes mellitus; Organ transplantation |
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Pharmacy > Department of Pharmaceutical Life Sciences |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 09 Jun 2022 03:20 |
| Last Modified: | 09 Jun 2022 03:20 |
| URI: | http://eprints.um.edu.my/id/eprint/34400 |
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