Recent advancements in polythiophene-based materials and their biomedical, geno sensor and DNA detection

Mousavi, Seyyed Mojtaba and Hashemi, Seyyed Alireza and Bahrani, Sonia and Yousefi, Khadije and Behbudi, Gity and Babapoor, Aziz and Omidifar, Navid and Lai, Chin Wei and Gholami, Ahmad and Chiang, Wei-Hung (2021) Recent advancements in polythiophene-based materials and their biomedical, geno sensor and DNA detection. International Journal of Molecular Sciences, 22 (13). ISSN 1661-6596, DOI https://doi.org/10.3390/ijms22136850.

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Abstract

In this review, the unique properties of intrinsically conducting polymer (ICP) in biomedical engineering fields are summarized. Polythiophene and its valuable derivatives are known as potent materials that can broadly be applied in biosensors, DNA, and gene delivery applications. Moreover, this material plays a basic role in curing and promoting anti-HIV drugs. Some of the thiophene's derivatives were chosen for different experiments and investigations to study their behavior and effects while binding with different materials and establishing new compounds. Many methods were considered for electrode coating and the conversion of thiophene to different monomers to improve their functions and to use them for a new generation of novel medical usages. It is believed that polythiophenes and their derivatives can be used in the future as a substitute for many old-fashioned ways of creating chemical biosensors polymeric materials and also drugs with lower side effects yet having a more effective response. It can be noted that syncing biochemistry with biomedical engineering will lead to a new generation of science, especially one that involves high-efficiency polymers. Therefore, since polythiophene can be customized with many derivatives, some of the novel combinations are covered in this review.

Item Type: Article
Funders: Ministry of Science and Technology of Taiwan (MOST)[MOST 107-2628-E-011002-MY3], Ministry of Science and Technology of Taiwan (MOST)[109-2923-E-011-003-MY3], Ministry of Science and Technology of Taiwan (MOST)[109-NU -E-011-001-NU0]
Uncontrolled Keywords: Polymers;Biochemistry;Antibacterial;Conductive polymers; Biosensors
Subjects: Q Science > QC Physics
Q Science > QD Chemistry
T Technology > TP Chemical technology
Divisions: Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre
Depositing User: Ms Zaharah Ramly
Date Deposited: 13 Sep 2022 02:47
Last Modified: 13 Sep 2022 02:47
URI: http://eprints.um.edu.my/id/eprint/34372

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