Functions of Burkholderia virulence factors: input from proteomics and DNA microarray analyses

Vellasamy, K.M. and Mariappan, V. and Hashim, Onn Haji and Vadivelu, J. (2012) Functions of Burkholderia virulence factors: input from proteomics and DNA microarray analyses. Journal of Analytical Science, 3 (1). pp. 72-80. ISSN 2093-3134

Full text not available from this repository. (Request a copy)

Abstract

Burkholderia spp. consists of organisms that are extremely diverse and versatile with a natural habitat in the soil. Members of this genus, which include B. pseudomallei, B. mallei, B. thailandensis and B. cepacia, are capable of causing severe, life threatening opportunistic infection in patients who are immunocompromised. The underlying virulence mechanisms of the bacteria, their interactions with the host and the host defense mechanisms may be reflected by changes of the expression of proteins of both the pathogen as well as the host. In this article, we reviewed the current knowledge on interactions of Burkholderia spp. pathogens with their host mainly from the perspective of data that was generated from recent proteomics and DNA microarray investigations.

Item Type: Article
Additional Information: Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords: Molecular Medicine
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Haslinda Lahuddin
Date Deposited: 06 Jul 2012 07:39
Last Modified: 24 Oct 2019 08:34
URI: http://eprints.um.edu.my/id/eprint/3425

Actions (login required)

View Item View Item