Khalid, Awais and Ahmad, Pervaiz and Alharthi, Abdulrahman I. and Muhammad, Saleh and Khandaker, Mayeen Uddin and Iqbal Faruque, Mohammad Rashed and Din, Israf Ud and Alotaibi, Mshari A. (2021) Unmodified titanium dioxide nanoparticles as a potential contrast agent in photon emission computed tomography. Crystals, 11 (2). ISSN 2073-4352, DOI https://doi.org/10.3390/cryst11020171.
Full text not available from this repository.Abstract
Highly crystalline titanium dioxide nanoparticles (TiO2-NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2-NPs are tested for improvement in two modes of kilovoltage radiation therapy and single-photon emission computed tomography (SPECT)/computed tomography (CT). Our results show that the unmodified TiO2-NPs provide an observable enhancement in CT scan image contrast ranging from 0 +/- 3 HU (without NPs) to 283.7 +/- 3 HU (0.23 g/mL). TiO2-NPs has excellent biocompatibility, selective uptake at target sites, and reduced toxicity. The unmodified TiO2-NPs as a contrast agent can significantly improve the existing methods of diagnosing and treating cancer.
| Item Type: | Article |
|---|---|
| Funders: | Research Universiti Grant, Universiti Kebangsaan Malaysia, Geran Universiti Penyelidikan (GUP)[2018-134] |
| Uncontrolled Keywords: | Nanoparticles;Titanium dioxide;Highly crystalline;Computed tomography |
| Subjects: | Q Science > QC Physics |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 18 Jul 2022 06:56 |
| Last Modified: | 18 Jul 2022 06:56 |
| URI: | http://eprints.um.edu.my/id/eprint/34098 |
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