Hariri, Firdaus and Farhana, Nurul Aiman and Abdullah, Norli Anida and Ibrahim, Norliza and Ramli, Norlisah Mohd and Abdullah, Azlindarita Aisyah Mohd and May, Choo May and Khaliddin, Nurliza (2021) Optic canal characteristics in pediatric syndromic craniosynostosis. Journal of Cranio-Maxillofacial Surgery, 49 (12). pp. 1175-1181. ISSN 1010-5182, DOI https://doi.org/10.1016/j.jcms.2021.06.017.
Full text not available from this repository.Abstract
The aim of this study was to compare optic canal parameters of syndromic craniosynostosis patients with those of normal patients to visit the possibility of optic nerve impingement as a cause of visual impairment. Computed tomography scan images were processed using the Materialise Interactive Medical Image Control System (MIMICS) Research 21.0 software (Materialise NV, Leuven, Belgium). Eleven optic canal parameters were measured: 1) height of optic canal on the cranial side, 2) height of optic canal on the orbital side 3) length of the medial wall of the optic canal, 4) length of the lateral canal wall of the optic canal, 5) diameter of the optic canal at five points (Q1-Q4 and mid canal), and 6) area and perimeter of optic canal. These measurements were obtained for both the right and left optic canals. The study sample comprised four Crouzon syndrome, five Apert syndrome, and three Pfeiffer syndrome patients. The age of these syndromic craniosynostosis patients ranged from 2 to 63 months. The height of the optic canal on the orbital side (p = 0.041), diameter of the mid canal (p = 0.040), and diameter between the mid-canal and the cranial opening (Q3) (p = 0.079) for syndromic craniosynostosis patients were statistically narrower compared with those of normal patients when a significance level of 0.1 was considered. Scatter plots for the ages of patients versus the above parameters gave three separated clusters that suggested the arresting of optic canal development with age. The findings from this study demonstrated a narrowing of the optic canal in syndromic craniosynostosis patients, and indicate that optic canal anatomical characteristics may have an association with visual impairment among pediatric syndromic craniosynostosis patients. (c) 2021 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya [Grant No: BKS081-2017] |
| Uncontrolled Keywords: | Syndromic craniosynostosis; Optic canal; Papilledema; Craniofacial surgery |
| Subjects: | R Medicine > RK Dentistry R Medicine > RK Dentistry > Oral surgery |
| Divisions: | Centre for Foundation Studies in Science Faculty of Dentistry Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 29 Jun 2022 07:56 |
| Last Modified: | 29 Jun 2022 07:56 |
| URI: | http://eprints.um.edu.my/id/eprint/33977 |
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