Cervical cancer burden, status of implementation and challenges of cervical cancer screening in Association of Southeast Asian Nations (ASEAN) countries

Zhao, Shuang and Huang, Liuye and Basu, Partha and Domingo, Efren Javier and Supakarapongkul, Wisit and Ling, Woo Yin and Ocviyanti, Dwiana and Rezhake, Remila and Qiao, Youlin and Tay, Eng Hseon and Zhao, Fanghui (2022) Cervical cancer burden, status of implementation and challenges of cervical cancer screening in Association of Southeast Asian Nations (ASEAN) countries. Cancer Letters, 525. pp. 22-32. ISSN 0304-3835, DOI https://doi.org/10.1016/j.canlet.2021.10.036.

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Abstract

Multiple barriers impede the transformation of evidence-based research into implementation of cervical cancer screening in ASEAN countries. This review is the first of its kind to show the disease burden of cervical cancer, progress till date to implement screening and corresponding challenges, and propose tailored solutions to promote cervical cancer prevention in ASEAN. In 2020, approximately 69 000 cervical cancer cases and 38 000 deaths happened in ASEAN, and more than 44% and 63% increases on new cases and deaths are expected in 2040. Only four countries have initiated population-based cervical cancer screening programs, but the participation rate is less than 50% in some countries and even lower than 10% in Myanmar and Indonesia. Inequity and unavailability in service delivery, lack of knowledge and awareness, limited follow-up and treatment capacity, and funding sustainability affect successful scale-up of cervical cancer screening most in ASEAN. Implementing HPV detection-based primary screening, appropriate management of screen-positives, enhancing health education, integrating health services can accelerate reduction of cervical cancer burden in ASEAN. Achieving high screening coverage and high treatment compliance will help ASEAN countries remain aligned to cervical cancer elimination strategies.

Item Type: Article
Funders: National Key R&D Program of China[2018YFC1315504], China Medical Board (CMB)[16-255]
Uncontrolled Keywords: HPV;Cervical cancer burden;Screening;Challenge;ASEAN
Subjects: R Medicine
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 25 Jul 2022 03:09
Last Modified: 25 Jul 2022 03:09
URI: http://eprints.um.edu.my/id/eprint/33708

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